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Eosinophilic granuloma is the mildest form of LCH which mainly affects the skull, mandible, ribs and femur in children and young adults but rarely occurs in the maxilla. Here, we describe an unusual case of eosinophilic granuloma affecting the tissues adjacent to tooth #25 and tooth #46 (FDI numbering system) in a 35\u2010year\u2010old male. Although lesions underwent clinical remission after local radiotherapy, a new lesion appeared 11\u00a0months after initial therapy in tooth #18, indicating recurrence of eosinophilic granuloma. Subsequently, the patient was treated with corticosteroid therapy, achieved remission and is disease free after 3\u00a0years of follow\u2010up.<\/jats:p>","DOI":"10.1111\/adj.12861","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T17:21:09Z","timestamp":1622136069000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent eosinophilic granuloma involving maxilla and mandible in an adult male: an unusual case report"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5932-1496","authenticated-orcid":false,"given":"X","family":"Xie","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu China"},{"name":"National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu China"},{"name":"Department of 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