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This patient was referred to the dental service for a suspected medication\u2010related osteonecrosis of the jaw (MRONJ). Clinically, the lesion was located underneath a fixed partial denture in the left posterior mandible. There was a purulent swelling on the lingual side of the fixed partial denture, and a hyperplastic exophytic lesion on the buccal side of the bridge. Panoramic radiograph showed a well circumscribed radiolucent lesion in the left mandible. A biopsy of the gingival lesion on the buccal aspect was inconclusive. As the positron emission tomography scan showed lytic lesions, oral manifestation of multiple myeloma could not be ruled out. A computed tomography\u2010guided biopsy of the left mandible showed plasma cell neoplasm in the histological analysis. Upon confirmed diagnosis, the patient was treated with 20Gy to the left mandible and subsequent debridement of the loose necrotic bone. Following treatment, this gingival lesion resolved completely, and the tumour has remained stable till date.<\/jats:p>","DOI":"10.1111\/adj.12882","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T16:16:42Z","timestamp":1635351402000},"page":"94-99","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Multiple myeloma masquerading as mandibular medication\u2010related osteonecrosis of the jaw: a case report"],"prefix":"10.1111","volume":"67","author":[{"given":"Y","family":"Danskin","sequence":"first","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Alhajji","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center  New York NY 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