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The heterogeneity of OSA necessitates a precision medicine approach to accurately diagnose this condition and to effectively manage patients. One of the primary models of precision medicine is described by the P4 approach of <jats:italic>predicting<\/jats:italic> those who are susceptible to disease, <jats:italic>preventing<\/jats:italic> the occurrence of disease, <jats:italic>personalizing<\/jats:italic> treatment, and encouraging patients to <jats:italic>participate<\/jats:italic> in their individual healthcare journey. Recent advances in oral appliance therapy and OSA monitoring techniques have fostered an exciting opportunity for enhanced collaboration between dentists and sleep physicians to optimize OSA precision medicine care. This review aims to discuss the sources of heterogeneity among OSA patients, provide an overview of the growing applications of oral appliance therapy and tailored monitoring programs for OSA that are shifting treatment to a more personalized and participatory model of care, and outline the pivotal role of dentists in managing patients with OSA.<\/jats:p>","DOI":"10.1111\/adj.13039","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T04:48:13Z","timestamp":1727844493000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Precision medicine approaches in obstructive sleep apnoea: The role of dentist\u2013sleep physician partnerships"],"prefix":"10.1111","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5383-0479","authenticated-orcid":false,"given":"GM","family":"Stewart","sequence":"first","affiliation":[{"name":"Charles Perkins Centre and Sydney Medical School 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