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A search strategy was followed to identify studies where any temporary anchorage devices contacted or were in proximity to tooth roots in humans. Studies with low possibility of bias and published in English or Latin\u2010character languages were considered for inclusion. Ten studies were identified; five case reports, one clinical study and four studies with intentional injury, totalling 736 temporary anchorage devices in 327 patients. Complications may ensue following temporary anchorage device placement, whether or not root contact occurs. Chronic apical periodontitis developed when there was root injury involving the pulp; necrosis can also occur. When damage was limited to the periodontal ligament, cementum or dentine, repair occurred, normally within 12\u00a0weeks. Clinicians should be aware of the potential for endodontic complications during temporary anchorage device placement, as well as during orthodontic treatment.<\/jats:p>","DOI":"10.1111\/aej.12375","type":"journal-article","created":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T11:43:26Z","timestamp":1571312606000},"page":"115-122","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Endodontic complications associated with orthodontic temporary anchorage devices: A systematic review of human studies"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8287-1226","authenticated-orcid":false,"given":"Giampiero","family":"Rossi\u2010Fedele","sequence":"first","affiliation":[{"name":"Adelaide Dental School The University of Adelaide Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5798-2584","authenticated-orcid":false,"given":"Gisele Jung","family":"Franciscatto","sequence":"additional","affiliation":[{"name":"Graduate Program in Dentistry School of Health and Life Sciences Pontifical Catholic University of Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil"},{"name":"Medical and Dental Centre of the Military Police of Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgina","family":"Marshall","sequence":"additional","affiliation":[{"name":"Adelaide Dental School The University of Adelaide Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0394-5400","authenticated-orcid":false,"given":"Maximiliano Sch\u00fcnke","family":"Gomes","sequence":"additional","affiliation":[{"name":"Graduate Program in Dentistry School of Health and Life Sciences Pontifical Catholic University of Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil"},{"name":"Medical and Dental Centre of the Military Police of Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9348-5817","authenticated-orcid":false,"given":"Esma J.","family":"Do\u011framac\u0131","sequence":"additional","affiliation":[{"name":"Adelaide Dental School The University of Adelaide Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,17]]},"reference":[{"issue":"721","key":"e_1_2_6_2_1","first-page":"e7","article-title":"Quantitative evaluation of cortical bone thickness with computed tomographic scanning for orthodontic implants","volume":"129","author":"Deguchi T","year":"2006","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01754.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2009.01453.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(95)70125-7"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jicd.12331"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2014.03.020"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjq047"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2319\/083107-405.1"},{"key":"e_1_2_6_10_1","first-page":"201","article-title":"Miniscrews as orthodontic anchorage: a preliminary report","volume":"13","author":"Costa A","year":"1998","journal-title":"Int J Adult Orthodon Orthognath Surg"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2012.03.015"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2012.09.011"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/14653125.2015.1114711"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.02.011"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjs025"},{"key":"e_1_2_6_16_1","first-page":"73","article-title":"Dental roots\u2019 and surrounding structures after contact with orthodontic mini\u2010implants: a systematic literature review","volume":"20","author":"Gintautait\u0117 G","year":"2018","journal-title":"Stomatologija"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000064"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-4-200908180-00135"},{"key":"e_1_2_6_19_1","unstructured":"The University of Adelaide The Joanna Briggs Institute.Checklist for Quasi\u2010Experimental Studies (non\u2010randomized experimental studies). 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