{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T16:39:53Z","timestamp":1788194393796,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T00:00:00Z","timestamp":1585872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Endodontic J"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mandibular molar teeth with acute irreversible pulpitis pose challenges in single visit root canal treatment \u2013 (i) success of local anaesthesia and (ii) post\u2010operative pain. One hundred and twenty\u2010six patients with pain associated with carious mandibular molar teeth were enrolled. All patients were administered 10\u00a0mg of ketorolac tromethamine prior to local anaesthesia. Local anesthetics used were 2% lignocaine with 1:80\u00a0000 adrenaline and 4% articaine with 1:100\u00a0000 adrenaline. Three irrigation solutions were used \u2013 saline, 3% sodium hypochlorite and dexamethasone. Mean intra\u2010operative pain scores for the lignocaine and articaine groups were 4.33 (\u00b12.58) and 4.22 (\u00b12.88), respectively. There was a statistically significant difference (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.000) in post\u2010operative pain incidence between the lignocaine and articaine groups with 16.7% (10 patients) and 49.2% (29 patients), respectively. Pre\u2010operative ketorolac tromethamine was not effective in reducing the intra\u2010operative pain incidence. However, it was effective in controlling post\u2010operative pain with lignocaine anesthetic group.<\/jats:p>","DOI":"10.1111\/aej.12407","type":"journal-article","created":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T16:21:24Z","timestamp":1585930884000},"page":"343-350","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Pre\u2010operative ketorolac efficacy with different anesthetics, irrigants during single visit root canal treatment of mandibular molars with acute irreversible pulpitis"],"prefix":"10.1111","volume":"46","author":[{"given":"V.","family":"Nivedha","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics CSI College of Dental Sciences Madurai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1261-9842","authenticated-orcid":false,"given":"I. 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