{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:34:22Z","timestamp":1747182862467,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T00:00:00Z","timestamp":1609977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Endodontic J"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The absence or presence of root resorption on the root surface of a replanted tooth indicates an immune\u2010inflammatory reaction. Since interleukin\u20106 (IL\u20106) is considered an inflammatory marker in bone resorption, this study aimed to investigate the association between clinical variables and polymorphisms in <jats:italic>IL6<\/jats:italic>, with the outcome of replanted teeth at 1\u2010year follow\u2010up. Altogether, 127 avulsed teeth that were replanted and had their root canals treated were selected for this study. Periapical radiographs were taken after replantation and after 1\u00a0year. Real\u2010time PCR was used to genotype <jats:italic>IL6<\/jats:italic> polymorphisms. Chi\u2010square and \u2018<jats:italic>Z<\/jats:italic>\u2019 tests were performed to verify the association between genetic variables and the prognosis of replanted teeth (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). An association was observed between the rs2069843 polymorphism of <jats:italic>IL6<\/jats:italic> and the outcome of replanted teeth (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The rs2069843 polymorphism of <jats:italic>IL6<\/jats:italic> may influence the outcome of avulsed and replanted teeth in the first year post\u2010trauma.<\/jats:p>","DOI":"10.1111\/aej.12483","type":"journal-article","created":{"date-parts":[[2021,1,10]],"date-time":"2021-01-10T18:33:45Z","timestamp":1610303625000},"page":"314-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The role of polymorphism of the <i>IL6<\/i> gene in tooth replantation"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2331-0090","authenticated-orcid":false,"given":"Liliane","family":"Roskamp","sequence":"first","affiliation":[{"name":"Curso de Odontologia Universidade Tuiuti do Paran\u00e1 Curitiba\u2010Paran\u00e1 Brazil"},{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5781-8629","authenticated-orcid":false,"given":"Paula Cristina","family":"Trevilatto","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0565-3492","authenticated-orcid":false,"given":"Cleber Machado","family":"Souza","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"},{"name":"Programa de pos Gradua\u00e7\u00e3o BIOTEC \u2013 Faculdades Pequeno Principe Instituto de Pesquisa Pel\u00e9 Pequeno Pr\u00edncipe Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8242-3781","authenticated-orcid":false,"given":"Sergio Aparecido","family":"Ign\u00e1cio","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5163-6047","authenticated-orcid":false,"given":"Giomo Dieila","family":"de Lima","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"},{"name":"Departamento de Bioci\u00eancias Faculdade de Odontologia de Piracicaba Universidade Estadual de Campinas S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1131-776X","authenticated-orcid":false,"given":"Tha\u00eds Munhoz","family":"Pereira","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2313-7117","authenticated-orcid":false,"given":"V\u00e2nia Portela Ditzel","family":"Westphalen","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/edt.12573"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2012.01125.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1995.tb00464.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090019"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/edt.12574"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3181ec112b"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.12.013"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720140140"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00415.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/gepi.20028"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402007000200012"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.4413105"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0126614100"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100084"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2007.10.051"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12384"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.05.006"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.06.027"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12797"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12196"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2014.130631"},{"issue":"2","key":"e_1_2_8_23_1","first-page":"43","article-title":"Serum interleukin\u20106 as a serologic marker of chronic periapical lesions: a case\u2010control study","volume":"2","author":"Abdolsamadi HR","year":"2008","journal-title":"J Dent Res Dent Clin Dent Prospects"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-9657.2003.00192.x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/324719"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2629"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2007.01272.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.20016.x"}],"container-title":["Australian Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aej.12483","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aej.12483","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aej.12483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T22:13:06Z","timestamp":1693347186000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aej.12483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,7]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/aej.12483"],"URL":"https:\/\/doi.org\/10.1111\/aej.12483","archive":["Portico"],"relation":{},"ISSN":["1329-1947","1747-4477"],"issn-type":[{"type":"print","value":"1329-1947"},{"type":"electronic","value":"1747-4477"}],"subject":[],"published":{"date-parts":[[2021,1,7]]},"assertion":[{"value":"2020-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}