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Ten bovine teeth were maintained in suspension in a container with the apical portion in contact with 0.2% agarose gel containing 0.1% metacresol purple. The canals were irrigated with 2.5% NaOCl, according to each irrigation protocol. After 3\u2009min, apical extrusion of NaOCl was observed by the colour gel change when in contact with NaOCl. The containers were photographed, and the NaOCl extrusion area was measured. All protocols showed NaOCl extrusion, providing similar area (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). Considering the similarity among the studied protocols, all of them can be considered during the endodontic treatment of immature teeth. Further studies on the particularities of immature teeth should be performed to evaluate cell viability, cleaning efficiency, disinfection capacity and dentin removal promoted by the irrigation protocols.<\/jats:p>","DOI":"10.1111\/aej.12574","type":"journal-article","created":{"date-parts":[[2021,10,9]],"date-time":"2021-10-09T16:56:11Z","timestamp":1633798571000},"page":"380-385","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Apical extrusion of sodium hypochlorite in immature teeth: comparison of three different cleaning protocols"],"prefix":"10.1111","volume":"48","author":[{"given":"Brenda Ai Refosco","family":"Takagi","sequence":"first","affiliation":[{"name":"Consevative Dentistry Department Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2514-6036","authenticated-orcid":false,"given":"Patr\u00edcia Maria Poli","family":"Kopper","sequence":"additional","affiliation":[{"name":"Consevative Dentistry Department Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"},{"name":"Graduate Dentistry Program Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana","family":"Luz","sequence":"additional","affiliation":[{"name":"Consevative Dentistry Department Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone Bonato","family":"Luisi","sequence":"additional","affiliation":[{"name":"Consevative Dentistry Department Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Kochenborger","family":"Scarparo","sequence":"additional","affiliation":[{"name":"Consevative Dentistry Department Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"},{"name":"Graduate Dentistry Program Dental School Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1992.tb00228.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4625-43.5.1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12606"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.05.006"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.01.016"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.09.021"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107bor-2019.vol33.0021"},{"key":"e_1_2_7_9_1","unstructured":"Easy e Bassi Equipamentos [Internet]. 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