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This study aims to compare the periapical healing at 1\u2010year follow\u2010up by evaluating newly generated trabecular bone with FA after Mineral trioxide aggregate (MTA) plug and regenerative endodontic treatment (RET). A total of 55 asymptomatic teeth with a single\u2010canal, open apex and periapical lesion, treated with MTA plug or RET, were evaluated retrospectively. After considering the inclusion\/exclusion criteria, FA was conducted on 30 periapical images using the box\u2010counting method. In both groups, a significant decrease was observed in the periapical lesion size at 1\u2010year follow\u2010up (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). However, there was no significant difference between the MTA plug and RET (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.01). Significantly higher fractal dimension values were detected at 1\u2010year follow\u2010up in both MTA plug and RET cases (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). However, the difference was not significant between the groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.01). Both procedures seem to improve periapical healing with a new resistant bone of similar density and complexity.<\/jats:p>","DOI":"10.1111\/aej.12697","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T15:19:45Z","timestamp":1664983185000},"page":"444-450","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Assessment of bone quality of apical periodontitis treated with <scp>MTA<\/scp> plug and regenerative endodontic techniques"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1124-1905","authenticated-orcid":false,"given":"Banu","family":"Aricioglu","sequence":"first","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry Recep Tayyip Erdo\u011fan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9607-6362","authenticated-orcid":false,"given":"Dilara 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