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This study aimed to evaluate the long\u2010term effects of iRoot BP Plus as an apical material in adult teeth. Fifty incisors and premolars were chosen for this study. All teeth were performed apical barrier with the same operator. After treatment, the teeth were clinically and radiographically evaluated at 1, 2 and 6\u2009years. At the 1\u2010year follow\u2010up, 35 teeth had healed, and three patients developed an apical abscess due to root fracture at the 2\u2010year follow\u2010up. Six years postoperatively, one tooth showed root resorption, which was considered a failure. The long clinical evaluation confirmed that iRoot BP Plus is a suitable material for the apical barrier of mature teeth with open apices and periapical lesions.<\/jats:p>","DOI":"10.1111\/aej.12815","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T23:58:25Z","timestamp":1700870305000},"page":"115-122","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Six\u2010year clinical evaluation of iRoot <scp>BP<\/scp> Plus as apical barrier in permanent teeth of periapical periodontitis"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1039-9559","authenticated-orcid":false,"given":"Lijun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Endodontics, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School Nanjing University  Nanjing 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