{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T00:20:55Z","timestamp":1776558055815,"version":"3.51.2"},"reference-count":60,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Endodontic J"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This systematic review aimed to compare the histological response of inflamed pulpodentinal complex to the hydraulic calcium silicate cements in experimental animal models of pulpitis. Articles that evaluated the histological response of inflamed pulp to mineral trioxide aggregate (MTA) in comparison with other restorative materials were selected and analysed in detail. The risk of bias assessment was conducted using SYRCLE's RoB tool. The GRADEpro tool was used to determine the overall quality of evidence. Out of the 2947 retrieved articles from databases, five articles fulfilled the inclusion criteria. MTA induced significantly more hard tissue formation compared to calcium hydroxide. The use of pulp\u2010capping material containing fluocinolone acetonide and ASP\/PLGA\u2010ASP\/ACP\/PLLA\u2010PLGA composite membrane was comparable. This systematic review could not demonstrate enhanced efficiency of capping materials compared to MTA. Future well\u2010conducted animal studies are warranted for demonstrating the hard tissue formation abilities of pulp\u2010capping materials with convenient inflammatory conditions.<\/jats:p>","DOI":"10.1111\/aej.12873","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T11:55:01Z","timestamp":1720094101000},"page":"729-741","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Histological response of inflamed pulp to hydraulic calcium silicate cements in direct pulp capping: Systematic review of pulpitis models"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9513-0841","authenticated-orcid":false,"given":"S\u0131la Nur","family":"Usta","sequence":"first","affiliation":[{"name":"Department of Endodontics, Gulhane Faculty of Dentistry University of Health Sciences  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8990-4847","authenticated-orcid":false,"given":"Cang\u00fcl","family":"Keskin","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry University of Ondokuz May\u0131s  Samsun Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burcu","family":"Pirimo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry University of Ondokuz May\u0131s  Samsun Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdurrahman","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology University of Ondokuz May\u0131s  Samsun Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/aej.12392"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12793"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13080"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13866"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2022.11.005"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13709"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2018.864"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12841"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12843"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2008.03.021"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.02.013"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2018.08.004"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513484336"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.10.012"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010020\u201003724\u20104"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2019.02.025"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600\u20109657.2001.170405.x"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.12.004"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678\u20107757\u20102019\u20100023"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2015.03.018"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/230251"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.08.010"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030\u20104220(63)90323\u20102"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.05.022"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102591.1980.tb00834.x"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13947"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102288\u201014\u201043"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.04.026"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2011.01.012"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2011.03.017"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.07.017"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2011.04.014"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.11.001"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/jfb13030106"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.22514\/jocpd.2023.057"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010126\u20105\u2010199703010\u201000006"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.30476\/dentjods.2019.81796.0"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/aej.12217"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.08.024"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.06.025"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.06.018"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2023.10.008"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010018\u20102767\u20105"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13683"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf02111285"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.14573\/altex.1406231"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fdmed.2021.673552"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrb.10035"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.5.2731"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/15476910601115150"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345920710051201"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910808700304"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u2010302X.2007.00310.x"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/794143"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2006.0116"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13449"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1093\/ilar\/ilu042"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187271"}],"container-title":["Australian Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aej.12873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T13:00:30Z","timestamp":1734008430000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aej.12873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,4]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/aej.12873"],"URL":"https:\/\/doi.org\/10.1111\/aej.12873","archive":["Portico"],"relation":{},"ISSN":["1329-1947","1747-4477"],"issn-type":[{"value":"1329-1947","type":"print"},{"value":"1747-4477","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,4]]},"assertion":[{"value":"2024-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}