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Accurate localization and minimal access to the root apex are paramount for successful outcomes and preservation of anatomical structures. Workflow considerations, such as three\u2010dimensional (3D) virtual planning and endodontic guidance represent new crucial aspects for addressing complex cases. This clinical case report presents the successful reintervention of a complex case using a Zekrya bur, operative microscopy, cone beam computed tomography and biocompatible materials. After a 48\u2010month follow\u2010up, complete healing of the treated area was observed. This minimally invasive technique, employing a simple instrument widely available globally, underscores the potential for efficient and predictable outcomes in complex endodontic microsurgical retreatment.<\/jats:p>","DOI":"10.1111\/aej.12884","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T04:56:35Z","timestamp":1724129795000},"page":"687-692","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Minimally invasive guided endodontic microsurgery with Zekrya bur: A 48\u2010month follow\u2010up case report"],"prefix":"10.1111","volume":"50","author":[{"given":"Lucas Moreira","family":"Maia","sequence":"first","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry Universidade de Ita\u00fana  Ita\u00fana Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil Moreira","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry Universidade de Ita\u00fana  Ita\u00fana Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson Renato Fran\u00e7a Alves","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius de Carvalho","family":"Machado","sequence":"additional","affiliation":[{"name":"Private Practice  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa Fassarela","family":"Marquiore","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry Federal University of Minas Gerais  Belo Horizonte Minas Gerais 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