{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T04:09:06Z","timestamp":1744776546696,"version":"3.40.4"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Endodontic J"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>This trial aimed to compare the success of mental\u2010incisive nerve blocks (MINB) on mandibular premolars with symptomatic irreversible pulpitis (SIP) after oral premedication using 10\u2009mg ketorolac or a placebo. One hundred and two patients were randomly divided into two groups. One hour prior to the administration of a MINB the patients were administered oral premedication's of either ketorolac or dextrose (placebo). The success of anaesthesia was verified by the absence of pain during the access cavity preparation or root canal instrumentation. Descriptive analysis was performed and categorical data were analysed using chi\u2010squared tests. Binary logistic regression was performed to assess the relationship among age, sex, type of premedication taken, preoperative pain score and tooth length to the pain outcome. The efficacy of MINB on mandibular premolars with SIP was not influenced significantly by the preoperative oral administration of ketorolac.<\/jats:p><jats:p><jats:bold>Trial Registration:<\/jats:bold> CTRI\/2021\/11\/038115<\/jats:p>","DOI":"10.1111\/aej.12924","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T13:08:56Z","timestamp":1739538536000},"page":"142-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of Premedication With Ketorolac on Anaesthetic Success of Mental\u2010Incisive Nerve Blocks With Symptomatic Irreversible Pulpitis: A Randomised Clinical Trial"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3783-3156","authenticated-orcid":false,"given":"Venkateshbabu","family":"Nagendrababu","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry, College of Dental Medicine University of Sharjah  Sharjah UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haritha Jamuna","family":"Subbarao","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College and Hospital Meenakshi Academy of Higher Education and Research (Deemed to Be University)  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parashar","family":"Saumya","sequence":"additional","affiliation":[{"name":"Private Practitioner  Dubai UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neeraj","family":"Menon","sequence":"additional","affiliation":[{"name":"Private Practitioner  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8396-2170","authenticated-orcid":false,"given":"Priyal","family":"Khandelwal","sequence":"additional","affiliation":[{"name":"Private Practitioner  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0726-7467","authenticated-orcid":false,"given":"Paul M. H.","family":"Dummer","sequence":"additional","affiliation":[{"name":"School of Dentistry, College of Biomedical and Life Sciences Cardiff University  Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2878-6837","authenticated-orcid":false,"given":"Velmurugan","family":"Natanasabapathy","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College and Hospital Meenakshi Academy of Higher Education and Research (Deemed to Be University)  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7870-1403","authenticated-orcid":false,"given":"Nandini","family":"Suresh","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College and Hospital Meenakshi Academy of Higher Education and Research (Deemed to Be University)  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.08.007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13697"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.02.015"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2500-4"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2019.06.008"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2011.0343"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.11.039"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.12.014"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12912"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.05.007"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/idj.12272"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(92)90233-P"},{"key":"e_1_2_8_14_1","first-page":"192","volume-title":"Essentials of Medical Pharmacology","author":"Tripathi K. D.","year":"2013"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13294"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2015.06.008"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1986.tb00119.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13416"},{"volume-title":"Handbook of Local Anesthesia","year":"2019","author":"Malamed S.","key":"e_1_2_8_19_1"},{"issue":"2","key":"e_1_2_8_20_1","article-title":"Effect of Oral Premedication on the Efficacy of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: A Prospective, Double\u2010Blind, Randomized Controlled Clinical Trial","volume":"10","author":"Saha S. G.","year":"2016","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-0707.108209"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199733060-00002"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2004.12.006"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2007.07.016"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.12.040"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)80849-6"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(98)80053-8"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13215"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2015.09.021"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13581"}],"container-title":["Australian Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aej.12924","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T04:27:43Z","timestamp":1744691263000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aej.12924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,14]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/aej.12924"],"URL":"https:\/\/doi.org\/10.1111\/aej.12924","archive":["Portico"],"relation":{},"ISSN":["1329-1947","1747-4477"],"issn-type":[{"type":"print","value":"1329-1947"},{"type":"electronic","value":"1747-4477"}],"subject":[],"published":{"date-parts":[[2025,2,14]]},"assertion":[{"value":"2024-11-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}