{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:48:16Z","timestamp":1792039696540,"version":"4.4.0"},"reference-count":115,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["HI20C2114"],"award-info":[{"award-number":["HI20C2114"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102021R1A2C2006952"],"award-info":[{"award-number":["NRF\u20102021R1A2C2006952"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102022M3A9F3082330"],"award-info":[{"award-number":["NRF\u20102022M3A9F3082330"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Endodontic J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Understanding the interfacial layer (IFL) between hydraulic calcium silicate cements (CSCs) and root dentine is essential for optimising CSC performance and developing next\u2010generation biomaterials. This scholarly review summarises current evidence on IFL composition, formation, structure, and clinical significance. An electronic search of PubMed, Web of Science, and Scopus identified relevant studies using 15 keywords, including \u2018interfacial layer.\u2019 A total of 115 articles were classified into three areas: CSC hydration, IFL formation and structure, and clinical implications. Evidence indicates that the IFL forms through hydration\u2010driven reactions and intratubular mineralisation, creating mechanical interlocking and chemical bonding that improve interfacial integrity and sealing ability. These interactions may reinforce dentine, reduce microleakage, and maintain antibacterial activity against intracanal microorganisms, thereby enhancing endodontic outcomes. Further well\u2010designed studies are needed to clarify the IFL's long\u2010term behaviour under clinical conditions and optimise interfacial stability while preserving dentine integrity.<\/jats:p>","DOI":"10.1111\/aej.70130","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:26:54Z","timestamp":1792038414000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hydraulic Calcium Silicate Cement\u2013Root Dentine Interfacial Layer"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7196-5123","authenticated-orcid":false,"given":"Yoon Seon","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry, Dental Research Institute Seoul National University Dental Hospital, Seoul National University School of Dentistry  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2285-6029","authenticated-orcid":false,"given":"Soojin","family":"Heo","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry National Health Insurance Service Ilsan Hospital  Goyang Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6484-5932","authenticated-orcid":false,"given":"Hiran","family":"Perinpanayagam","sequence":"additional","affiliation":[{"name":"Division of Endodontics Schulich School of Medicine &amp; Dentistry, University of Western Ontario  London Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5982-3616","authenticated-orcid":false,"given":"Yu","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Endodontics, School and Hospital of Stomatology, Cheeloo College of Medicine Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5945-1434","authenticated-orcid":false,"given":"Yoshi","family":"Terauchi","sequence":"additional","affiliation":[{"name":"Private Practice, CT &amp; Micro\u2010Endodontic Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6016-9436","authenticated-orcid":false,"given":"Chengfei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Endodontics, Restorative Dental Sciences, HKU Faculty of Dentistry The University of Hong Kong  Pok Fu Lam Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0932-3143","authenticated-orcid":false,"given":"Jong Ryul","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Endodontics Kornberg School of Dentistry, Temple University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Endodontics, School of Dental Medicine University of Connecticut  Farmington Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbasali","family":"Khademi","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Dental Research Center, Dental Research Institute, School of Dentistry Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010Sang","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Oral Maxillofacial Surgery Seoul National University Dental Hospital, Seoul National University School of Dentistry  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3032-3498","authenticated-orcid":false,"given":"Kee\u2010Yeon","family":"Kum","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry, Dental Research Institute Seoul National University Dental Hospital, Seoul National University School of Dentistry  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0099-2399(99)80142-3","article-title":"Clinical Applications of Mineral Trioxide Aggregate","volume":"25","author":"Torabinejad M.","year":"1999","journal-title":"Journal of Endodontics"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/j.joen.2011.08.020","article-title":"Heavy Metal Analysis of OrthoMTA and ProRoot MTA","volume":"37","author":"Chang S. 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