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A genetic component contributes to the development of this anomaly in Entlebucher mountain dogs (<jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content>); however, its nature remains unclear. Using the Illumina Canine<jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> bead chip, a case\u2013control genome\u2010wide association study was performed to identify <jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content>s associated with the trait. Six loci on canine chromosomes 3, 17, 27 and 30 were identified with 16 significantly associated <jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content>s. There was no single outstanding <jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content> associated with the phenotype, and the association signals were not close to known genes involved in human congenital anomalies of the kidney or lower urinary tract. Additional research will be necessary to elucidate the potential role of the associated genes in the development of ectopic ureters in the <jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content> breed.<\/jats:p>","DOI":"10.1111\/age.12728","type":"journal-article","created":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T07:46:05Z","timestamp":1538466365000},"page":"645-650","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Genome\u2010wide association study and heritability estimate for ectopic ureters in Entlebucher mountain dogs"],"prefix":"10.1111","volume":"49","author":[{"given":"M.","family":"Gallana","sequence":"first","affiliation":[{"name":"Clinic for Reproductive Medicine Vetsuisse\u2010Faculty University of Zurich Winterthurerstrasse 260 8057 Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. 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