{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:22:57Z","timestamp":1787167377000,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,3,10]],"date-time":"2019-03-10T00:00:00Z","timestamp":1552176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["OD 010939"],"award-info":[{"award-number":["OD 010939"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Genetics"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    In domestic cats, the\n                    <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>\n                    blood group system consists of the three types A, B and C (also called\n                    <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>\n                    ). Mismatches can cause acute hemolytic transfusion reactions and hemolysis of the newborn (neonatal isoerythrolysis,\n                    <jats:styled-content style=\"fixed-case\">NI<\/jats:styled-content>\n                    ). As blood types B and C are inherited recessively to A, breeders need to know the genotype to predict blood types in offspring and avoid\n                    <jats:styled-content style=\"fixed-case\">NI<\/jats:styled-content>\n                    . Several\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">CMAH<\/jats:styled-content>\n                    <\/jats:italic>\n                    variants have been described as being associated with the\n                    <jats:italic>b<\/jats:italic>\n                    and\n                    <jats:italic>a<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>c<\/jats:italic>\n                    <\/jats:sup>\n                    alleles, and different genotyping schemes exist. Here, we genotyped 2145 cats with the original\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    panel, including\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    s c.142G&gt;A and \u2206\u201053, and our new scheme, with\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    s c.179G&gt;T, c.268T&gt;A and c.1322delT, to differentiate types A and B and added the\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    for the common\n                    <jats:italic>a<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>c<\/jats:italic>\n                    <\/jats:sup>\n                    (c.364C&gt;T). Based upon the new scheme, all samples were assigned the correct genotype. No discordances appeared for the\n                    <jats:italic>A<\/jats:italic>\n                    allele, and new breed\u2010specific\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    s (c.179G&gt;T, c.1322delT) for the\n                    <jats:italic>b<\/jats:italic>\n                    allele were discovered. Furthermore, the genotypes\n                    <jats:italic>A\/<\/jats:italic>\n                    a\n                    <jats:sup>c<\/jats:sup>\n                    (type A),\n                    <jats:italic>a<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>c<\/jats:italic>\n                    <\/jats:sup>\n                    <jats:italic>\/a<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>c<\/jats:italic>\n                    <\/jats:sup>\n                    (C) and\n                    <jats:italic>a<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>c<\/jats:italic>\n                    <\/jats:sup>\n                    <jats:italic>\/b<\/jats:italic>\n                    (C) could be detected. We found the variant c.179G&gt;T in additional breeds: Ragdoll, Siberian, Scottish Fold, Chartreux, Neva Masquerade, British Shorthair and Highlander. Also, the variant c.364C&gt;T was detected in additional breeds: Bengal, British Shorthair, Maine Coon, and Scottish Fold. We conclude that our new\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    panel is superior in genotyping cats than the original\n                    <jats:styled-content style=\"fixed-case\">SNV<\/jats:styled-content>\n                    panel and assures correct assignments of types A, B and C to assist veterinary clinicians and breeders to recognize, confirm and avoid blood incompatibilities such as acute hemolytic transfusion reactions and\n                    <jats:styled-content style=\"fixed-case\">NI<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/age.12778","type":"journal-article","created":{"date-parts":[[2019,3,11]],"date-time":"2019-03-11T02:45:51Z","timestamp":1552272351000},"page":"303-306","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["<i>\n                      <scp>CMAH<\/scp>\n                    <\/i>\n                    genotyping survey for blood types A, B and C (\n                    <scp>AB<\/scp>\n                    ) in purpose\u2010bred cats"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1547-0713","authenticated-orcid":false,"given":"A.","family":"Kehl","sequence":"first","affiliation":[{"name":"Laboklin Steubenstra\u00dfe 4 Bad Kissingen D\u201097688 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Laboklin Steubenstra\u00dfe 4 Bad Kissingen D\u201097688 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Giger","sequence":"additional","affiliation":[{"name":"Section\u00a0of Medical Genetics (PennGen) Section of Medical Genetics (PennGen) School of Veterinary Medicine University of Pennsylvania 3900 Delancey Street Philadelphia PA 19104\u20106010 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2052.1981.tb01561.x"},{"key":"e_1_2_4_3_1","first-page":"729","article-title":"Blood transfusion reactions in the cat","volume":"180","author":"Auer L.","year":"1982","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2156-8-27"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2007.00325.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0154973"},{"key":"e_1_2_4_7_1","volume-title":"Kirk's Current Veterinary Therapy XV","author":"Giger U.","year":"2014"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jhered\/82.1.15"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(95)50156-1"},{"key":"e_1_2_4_10_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/BF03548338","article-title":"Distribution of feline blood types detected in the Copenhagen area of Denmark","volume":"35","author":"Jensen A.L.","year":"1994","journal-title":"Acta Veterinaria Scandinavica"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204287"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1999.tb03051.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165000"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/704836"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12180"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/2055116917727693"},{"key":"e_1_2_4_17_1","first-page":"189","article-title":"Pr\u00e4valenz der blutgruppen A, B und AB bei haus\u2010 und rassekatzen im raum Berlin und Brandenburg","volume":"51","author":"Weingart C.","year":"2006","journal-title":"Kleintierpraxis"}],"container-title":["Animal Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fage.12778","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/age.12778","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/age.12778","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/age.12778","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T07:28:23Z","timestamp":1694330903000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/age.12778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,10]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1111\/age.12778"],"URL":"https:\/\/doi.org\/10.1111\/age.12778","archive":["Portico"],"relation":{},"ISSN":["0268-9146","1365-2052"],"issn-type":[{"value":"0268-9146","type":"print"},{"value":"1365-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,10]]},"assertion":[{"value":"2019-01-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}