{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:36:09Z","timestamp":1747182969440,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,7,17]],"date-time":"2022-07-17T00:00:00Z","timestamp":1658016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Genetics"],"published-print":{"date-parts":[[2022,10]]},"abstract":"Abstract<\/jats:title>Sno\u2010lncRNAs<\/jats:italic> are intron\u2010derived long noncoding RNAs (lncRNAs) with snoRNA ends. Sno\u2010lncRNAs<\/jats:italic> were first discovered in the human Prader\u2013Willi (PWS)\/Angelman (AS) imprinted domain. Here, we report the identification and characterization of four sno\u2010lncRNA<\/jats:italic> types (sno\u2010lncRNA1<\/jats:italic>, sno\u2010lncRNA2<\/jats:italic>, sno\u2010lncRNA3<\/jats:italic>, and sno\u2010lncRNA4<\/jats:italic>) in the bovine PWS\/AS<\/jats:italic> imprinted domain.<\/jats:italic> Reverse transcription\u2013PCR first determined the cDNA sequences of the four bovine sno\u2010lncRNAs<\/jats:italic>. A gene structure analysis showed that sno\u2010lncRNA1<\/jats:italic> lacks introns, but sno\u2010lncRNA2<\/jats:italic> and sno\u2010lncRNA3<\/jats:italic> have one and two introns respectively. The three sno\u2010lncRNAs<\/jats:italic> have similar snoRNA ends. Moreover, the three have similar snoRNAs at their 5\u2032 and 3\u2032 ends. The head\u2010to\u2010tail orientation has six sno\u2010lncRNA<\/jats:italic> copies arranged between bovine SNORD116\u20106<\/jats:italic> and SNORD116\u201012.<\/jats:italic> Moreover, only a copy of sno\u2010lncRNA4<\/jats:italic> was located between SNORD116\u20103<\/jats:italic> and SNORD116\u20104.<\/jats:italic> The expression of the four sno\u2010lncRNAs<\/jats:italic> was analyzed in the bovine heart, liver, spleen, lung, kidney, muscle, fat, brain, and placenta tissues. The monoallelic expression of sno\u2010lncRNA4<\/jats:italic> was determined in bovine tissues. The results showed that the four sno\u2010lncRNAs<\/jats:italic> are widely expressed in the nine tissues, although sno\u2010lncRNA3<\/jats:italic> and sno\u2010lncRNA4<\/jats:italic> were undetected in the placenta. Moreover, an informative single nucleotide polymorphism (rs448706424) revealed the allelic expression of sno\u2010lncRNA4<\/jats:italic> in exon 2 of sno\u2010lncRNA4.<\/jats:italic> The bovine genome had six copies of sno\u2010lncRNA1<\/jats:italic>, sno\u2010lncRNA2<\/jats:italic>, and sno\u2010lncRNA3<\/jats:italic>, but their allelic expression was not identified.<\/jats:p>","DOI":"10.1111\/age.13244","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T03:13:30Z","timestamp":1658114010000},"page":"685-689","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The bovine Prader\u2013Willi<\/scp>\/Angelman imprinted domain has four Sno\u2010lncRNAs<\/i><\/scp> types"],"prefix":"10.1111","volume":"53","author":[{"given":"Weina","family":"Chen","sequence":"first","affiliation":[{"name":"College of Traditional Chinese Medicine Hebei University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Ma","sequence":"additional","affiliation":[{"name":"Baoding NO.2 Hospital Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanqiu","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, College of Life Science Hebei Agriculture University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4854-6590","authenticated-orcid":false,"given":"Shijie","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, College of Life Science Hebei Agriculture University Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9084(02)01402-5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genet-110410-132459"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a002592"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2014.103"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2184"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.0b013e31822bead0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.5"},{"key":"e_1_2_6_9_1","first-page":"1067","article-title":"Small evolutionarily conserved RNA, resembling C\/D box small nucleolar RNA, is transcribed from PWCR1, a novel imprinted gene in the Prader\u2010Willi deletion region, which is highly expressed in brain","volume":"67","author":"Santos T.","year":"2000","journal-title":"Human Genetics"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp263"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2010.102"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.14.3617"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2124"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.4.5.9242"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1042\/BC20070126"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.158"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2011.02.018"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/415810a"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2011.08.018"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.04.011"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2012.07.033"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.09.001"}],"container-title":["Animal Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/age.13244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/age.13244","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/age.13244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T06:59:05Z","timestamp":1692773945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/age.13244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,17]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/age.13244"],"URL":"https:\/\/doi.org\/10.1111\/age.13244","archive":["Portico"],"relation":{},"ISSN":["0268-9146","1365-2052"],"issn-type":[{"type":"print","value":"0268-9146"},{"type":"electronic","value":"1365-2052"}],"subject":[],"published":{"date-parts":[[2022,7,17]]},"assertion":[{"value":"2022-02-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}