{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T01:22:26Z","timestamp":1791508946149,"version":"4.3.4"},"reference-count":173,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000837","name":"University of Nottingham","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000837","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Genetics"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Environmental adaptation traits of indigenous African cattle are increasingly being investigated to respond to the need for sustainable livestock production in the context of unpredictable climatic changes. Several studies have highlighted genomic regions under positive selection probably associated with adaptation to environmental challenges (e.g. heat stress, trypanosomiasis, tick and tick\u2010borne diseases). However, little attention has focused on pinpointing the candidate causative variant(s) controlling the traits. This review compiled information from 22 studies on signatures of positive selection in indigenous African cattle breeds to identify regions under positive selection. We highlight some key candidate genome regions and genes of relevance to the challenges of living in extreme environments (high temperature, high altitude, high infectious disease prevalence). They include candidate genes involved in biological pathways relating to innate and adaptive immunity (e.g.\n                    <jats:italic>BoLAs<\/jats:italic>\n                    ,\n                    <jats:italic>SPAG11<\/jats:italic>\n                    ,\n                    <jats:italic>IL1RL2<\/jats:italic>\n                    and\n                    <jats:italic>GFI1B<\/jats:italic>\n                    ), heat stress (e.g.\n                    <jats:italic>HSPs<\/jats:italic>\n                    ,\n                    <jats:italic>SOD1<\/jats:italic>\n                    and\n                    <jats:italic>PRLH<\/jats:italic>\n                    ) and hypoxia responses (e.g.\n                    <jats:italic>BDNF<\/jats:italic>\n                    and\n                    <jats:italic>INPP4A<\/jats:italic>\n                    ). Notably, the highest numbers of candidate regions are found on BTA3, BTA5 and BTA7. They overlap with genes playing roles in several biological functions and pathways. These include but are not limited to growth and feed intake, cell stability, protein stability and sweat gland development. This review may further guide targeted genome studies aiming to assess the importance of candidate causative mutations, within regulatory and protein\u2010coding genome regions, to further understand the biological mechanisms underlying African cattle's unique adaption.\n                  <\/jats:p>","DOI":"10.1111\/age.13353","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T02:39:08Z","timestamp":1694486348000},"page":"689-708","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Candidate signatures of positive selection for environmental adaptation in indigenous African cattle: A review"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3093-7251","authenticated-orcid":false,"given":"Sumaya","family":"Kambal","sequence":"first","affiliation":[{"name":"Livestock Genetics International Livestock Research Institute Addis Ababa Ethiopia"},{"name":"Department of Genetics and Animal Breeding, Faculty of Animal Production University of Khartoum Khartoum Sudan"},{"name":"Department of Bioinformatics and Biostatistics National University Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0793-9059","authenticated-orcid":false,"given":"Abdulfatai","family":"Tijjani","sequence":"additional","affiliation":[{"name":"Centre for Tropical Livestock Genetics and Health International Livestock Research Institute Addis Ababa Ethiopia"},{"name":"The Jackson Laboratory Bar Harbor Maine USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2908-3658","authenticated-orcid":false,"given":"Sabah A. E.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics and Biostatistics National University Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed\u2010Khair A.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Genetics and Animal Breeding, Faculty of Animal Production University of Khartoum Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joram M.","family":"Mwacharo","sequence":"additional","affiliation":[{"name":"Scotland's Rural College and Centre for Tropical Livestock Genetics and Health Edinburgh UK"},{"name":"Small Ruminant Genomics International Centre for Agricultural Research in the Dry Areas Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2877-4767","authenticated-orcid":false,"given":"Olivier","family":"Hanotte","sequence":"additional","affiliation":[{"name":"Livestock Genetics International Livestock Research Institute Addis Ababa Ethiopia"},{"name":"Centre for Tropical Livestock Genetics and Health International Livestock Research Institute Addis Ababa Ethiopia"},{"name":"School of Life Sciences University of Nottingham Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes13010050"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02250871"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2020.00544"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003110"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002992"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1071\/BI9680303"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.106.059626"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0202479"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep11729"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0190446"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2017.00068"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12192\u2010011\u20100257\u20107"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.2527\/2006.844972x"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2018.214"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12379"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201076576\u20103"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0126498"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40121\u2010014\u20100030\u20101"},{"key":"e_1_2_12_20_1","volume-title":"The origins and development of African livestock: archaeology, genetics, linguistics and ethnography","author":"Blench R.","year":"1999"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1167936"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.10.5131"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102052.1994.tb00440.x"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1203"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0368\u20101742(58)80025\u20109"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00484\u2010021\u201002083\u20103"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.3892\/br.2012.48"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2018.00607"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201095816\u20108"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u2010185X.2011.00177.x"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010animal\u2010022114\u2010110659"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1117213109"},{"key":"e_1_2_12_33_1","volume-title":"Domestic animal genetic resources information system (DAGRIS)","author":"DAGRIS","year":"2007"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2016.0956"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114514003535"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes9090430"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01019"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.20506\/rst.17.1.1088"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12162133"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356\u2010021\u201014077\u20100"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2013.00035"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/jbg.12083"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102052.2007.01638.x"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2020.104314"},{"key":"e_1_2_12_45_1","volume-title":"The origin of the domestic animals of Africa","author":"Epstein H.","year":"1971"},{"key":"e_1_2_12_46_1","volume-title":"Evolution of domesticated animals","author":"Epstein H.","year":"1984"},{"key":"e_1_2_12_47_1","unstructured":"Esri Inc. (2019)ArcGIS (version: 10.7.1). Available from:www.esri.com[Accessed 9 March 2023]."},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1471\u20104922(00)01846\u20108"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14972"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/155.3.1405"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.3390\/d6040705"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/joc.5086"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2007.2171"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/age.13027"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.12816"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u2010294X.2004.02311.x"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/age.12900"},{"key":"e_1_2_12_58_1","first-page":"163","volume-title":"Prehistory of arid North Africa. Essays in Honor of Fred Wendorf","author":"Gautier A.","year":"1987"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102164\u201010\u2010550"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.2527\/2001.7971757x"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010022\u201005617\u20109"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msab156"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10963\u2010010\u20109042\u20102"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.107196"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201014535"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01117218"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.106.063107"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13339"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15476"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1069878"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1232392100"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u2010294x.2000.00858.x"},{"key":"e_1_2_12_73_1","first-page":"333","article-title":"Effects of coat colour on physiological responses to solar radiation in Holsteins","volume":"127","author":"Hansen P.J.","year":"1990","journal-title":"Veterinary Record"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2004.04.011"},{"key":"e_1_2_12_75_1","first-page":"86","volume-title":"The first steps of animal domestication: new archaeozoological approaches","author":"Helmer D.","year":"2005"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00484\u2010018\u20101629\u20109"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2010.02.002"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2019.00357"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2006.06.006"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010021\u201007808\u20107"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.79387"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/jbg.12648"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2941"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.2009.68"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.723360"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059\u2010017\u20101153\u2010y"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588\u2010020\u20100694\u20102"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010017\u20103742\u20102"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI70720"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2021.0198"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.10.013"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.909012"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1127\/0941\u20102948\/2006\/0130"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2010.12.021"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915\u2010021\u201001206\u2010x"},{"key":"e_1_2_12_96_1","first-page":"95","article-title":"Regulation of epithelial Na channels by aldosterone: role of Sgk1","volume":"38","author":"Lee I.H.","year":"2007","journal-title":"Proceedings of the Australian Physiological Society"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2006.04.035"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.2307\/j.ctv2n37kdx.14"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6861"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.7.2757"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201015848\u2010y"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102164\u201011\u2010280"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010animal\u2010022516\u2010022747"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/146.3.1071"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2014.00333"},{"key":"e_1_2_12_106_1","unstructured":"Mapholi N.O.(2015)Exploring genetic architecture of tick resistance in South African Nguni cattle. Dissertation Stellenbosch University."},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1051\/gse:2002039"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2011.07.001"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001\u2010706X(00)00063\u20102"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.10607"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010022\u201008512\u2010w"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0000000000000112"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.130336711"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2019.01095"},{"key":"e_1_2_12_115_1","first-page":"216","article-title":"Effect of climate change on dairy production in Botswana and its suitable mitigation strategies","volume":"3","author":"Moreki J.C.","year":"2013","journal-title":"Online Journal of Animal and Feed Research"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/149.3.311"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.15.0002R"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749\u20106632.1998.tb11049.x"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2019.06.002"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1071\/AR9560482"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.5897\/AJAR11.1468"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.4252305"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1013486108"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102164\u201010\u2010207"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2009.0219"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1186\/1753\u20106561\u20105\u2010S4\u2010S23"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.09.008"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1071\/AR9630424"},{"key":"e_1_2_12_129_1","first-page":"29","article-title":"Extreme ambiences vis\u2010\u00e0\u2010vis endogenous antioxidants of Marwari goat from arid tracts in India","volume":"4","author":"Pandey N.","year":"2014","journal-title":"Extreme Life, Biospeology and Astrobiology"},{"key":"e_1_2_12_130_1","first-page":"51","volume-title":"Cattle genetic resources","author":"Payne W.J.A.","year":"1991"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtherbio.2014.08.004"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102052.2009.01988.x"},{"key":"e_1_2_12_133_1","first-page":"148","volume-title":"Investing in animal health research to alleviate poverty","author":"Perry B.D.","year":"2002"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003011"},{"key":"e_1_2_12_135_1","volume-title":"JBI manual for evidence sythesis","author":"Peters M.D.J.","year":"2020"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102156\u20106\u201034"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2010.01.012"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/eva.12674"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdf505"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2018.00057"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2014.05.003"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153013"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1014233900003448"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1014233900001152"},{"key":"e_1_2_12_145_1","first-page":"57","volume-title":"Food security in Africa. Chellenges, opportunities and target for animal production","author":"Rege J.E.O.","year":"1996"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201040576\u20109"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.959102"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2020.104257"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.13270"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2022\u201022272"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201028605\u20100"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1080\/23311932.2018.1552552"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1111\/asj.12851"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00335\u2010017\u20109715\u20106"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.960234"},{"key":"e_1_2_12_156_1","unstructured":"Tijjani A.(2019)Genome diversity and adaptation of African taurine and zebu cattle. Doctoral dissertation University of Nottingham."},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2022.110423"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2019.00442"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2015.00036"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.3389\/fevo.2022.866587"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2020.608650"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aav1002"},{"key":"e_1_2_12_163_1","first-page":"389","article-title":"Haircoat characteristics and tick infestation on gyr (zebu) and crossbred (holdstein x gyr) cattle","volume":"51","author":"Verissimo C.J.","year":"2002","journal-title":"Archivos de Zootecnia"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304\u20104017(97)00229\u2010X"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.104672"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.1093\/zoolinnean\/zly007"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evab014"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.2012.9"},{"key":"e_1_2_12_169_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071393"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559\u2010018\u20100562\u2010y"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2010.12.005"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5439.525"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0003598X00068952"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.10.100"}],"container-title":["Animal Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/age.13353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T08:47:22Z","timestamp":1699001242000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/age.13353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,11]]},"references-count":173,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1111\/age.13353"],"URL":"https:\/\/doi.org\/10.1111\/age.13353","archive":["Portico"],"relation":{},"ISSN":["0268-9146","1365-2052"],"issn-type":[{"value":"0268-9146","type":"print"},{"value":"1365-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,11]]},"assertion":[{"value":"2023-07-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}