{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:24:41Z","timestamp":1740126281617,"version":"3.37.3"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,7,29]],"date-time":"2018-07-29T00:00:00Z","timestamp":1532822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Veterinary team of Cairo slaughterhouse"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Progesterone receptors (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>) are necessary to mediate the biological effects of progesterone and are integral to the regulation of a number of different aspects of reproduction in mammals including ovulation of the oocyte, implantation of the conceptus and maintenance of pregnancy. This study investigated the expression and localization of progesterone receptors in the uterine wall of both pregnant and cyclic (nonpregnant) camels. Uterine tissue samples were collected from healthy animals and processed for routine histological and immunohistochemical staining techniques to reveal nuclear <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>. Demonstration of <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> was performed by indirect immunohistochemical techniques using monoclonal antibodies raised against human <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>. Immunolocalization of <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> was more intense in all four endometrial zones (I\u2013<jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>) as well as the myometrium of non pregnant (cyclic) animals (animals with newly formed corpus luteum). In contrast, <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> immunostaining in both the endometrium and the myometrium was greatly reduced in pregnancy, particularly in the latest stage examined (approximately 366\u00a0days of gestation). In conclusion, a better understanding of the expression of steroid hormones and their receptors, including progesterone and the <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> is critical to improving the reproductive health and pregnancy in the domesticated dromedary camel.<\/jats:p>","DOI":"10.1111\/ahe.12395","type":"journal-article","created":{"date-parts":[[2018,7,30]],"date-time":"2018-07-30T06:04:43Z","timestamp":1532930683000},"page":"544-550","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Survey of nuclear progesterone receptor expression in the uterus of the cyclic and pregnant camel (<i>Camelus dromedarius<\/i>)"],"prefix":"10.1111","volume":"47","author":[{"given":"Abdel\u2010Hamid K.","family":"Osman","sequence":"first","affiliation":[{"name":"Department of Cytology &amp; Histology Faculty of Veterinary Medicine Suez Canal University  Ismailia Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1523-1130","authenticated-orcid":false,"given":"Louise C.","family":"Abbott","sequence":"additional","affiliation":[{"name":"Department of Veterinary Integrative Biosciences College of Veterinary Medicine and Biomedical Sciences Texas A&amp;M University  College Station Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal A. 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