{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T19:04:37Z","timestamp":1788980677825,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T00:00:00Z","timestamp":1563148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The proximal caecum in quails consists of lymphoid and non\u2010lymphoid structures. The caecal tonsils in the proximal part of the caecum are units of gut\u2010associated lymphoid tissue in poultry. This study aimed to examine the histological characteristics of the proximal caecum, as well as compositions of dendritic cells (DCs) and antigen\u2010presenting cells (APCs) in the caecal tonsil of quails. Tissue sections were stained with Crossman's triple, periodic acid\u2013Schiff, Gordon and Sweet's silver, Congo red and methyl green\u2010pyronin dyes, as well as immunohistochemically by the streptavidin\u2013biotin\u2013peroxidase complex method. Caecal lymphoid tissue was located in the lamina propria and submucosa. Germinative centres were observed within the lymphoid tissue. Reticular fibres were mainly distributed in the border area of the germinal centre with only a few fibres scattered in the centre. Plasma cells were observed in the subepithelial region and germinal centres. Eosinophil granulocytes were prevalent in the lymphoid tissue. Additionally, CD83\u2010immunoreactive DCs and MHC class II immunoreactive APCs were present in the subepithelial area and diffuse lymphoid tissue. While DCs were seen in the germinal centres of tonsillar units, APCs were rarely present in the germinal centres, but they were noticed around the germinal centres. In conclusion, the histological structure of the proximal caecum in quails and the distributions of some immunological cells in the caecal tonsils were revealed. Therefore, the defensive role of the caecal tonsils in the digestive system may be better understood, and comparative studies may be carried out.<\/jats:p>","DOI":"10.1111\/ahe.12469","type":"journal-article","created":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T14:01:09Z","timestamp":1563199269000},"page":"476-485","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Histological and immunohistochemical studies of the proximal caecum and caecal tonsils of quail (<i>Coturnix coturnix japonica<\/i>)"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4128-8947","authenticated-orcid":false,"given":"Mustafa","family":"Yildiz","sequence":"first","affiliation":[{"name":"Department of Occupational Health and Safety, \u00c7an School of Applied Sciences \u00c7anakkale Onsekiz Mart University Canakkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isil","family":"Aydemir","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Medicine Ni\u011fde \u00d6mer Halisdemir University Nigde Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadiye","family":"Kum","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Veterinary Medicine Ayd\u0131n Adnan Menderes University Aydin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulker","family":"Eren","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Veterinary Medicine Ayd\u0131n Adnan Menderes University Aydin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3329\/bjvm.v4i2.1289"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1076071"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/18069061-2015-0035"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079451003786105"},{"key":"e_1_2_5_6_1","volume-title":"Practical section cutting and staining","author":"Clayden E.","year":"1971"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-010X(19990301\/01)283:4\/5<441::AID-JEZ13>3.0.CO;2-8"},{"issue":"1","key":"e_1_2_5_8_1","first-page":"93","article-title":"The avian cecum: A review","volume":"107","author":"Clench M. 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