{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T17:37:13Z","timestamp":1783705033779,"version":"3.55.0"},"reference-count":65,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T00:00:00Z","timestamp":1597276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Sheep are recognized as useful species for translational neurodegeneration research, in particular for the study of Huntington disease. There is a lack of information regarding the detailed anatomy and connections of the basal ganglia of sheep, in normal myeloarchitectonics and in tract\u2010tracing studies. In this work, the organization of the corticostriatal projections at the level of the putamen and globus pallidus (GP) are explored. For the first time, the myeloarchitectonic pattern of connections between the internal (IC) and the external (EC) capsules with the GP have been investigated in the sheep. Formaldehyde\u2010fixed blocks of the striatum were treated with a metallic stain containing potassium dichromate and visualized using micro\u2010CT (\u00b5\u2010CT). The trivalent chromium (Cr3+), attached to myelin phospholipids, imparts a differential contrast to the grey and white matter compartments, which allows the visualization of myelinated fascicles in \u00b5\u2010CT images. The fascicles were classified according to their topographical location in dorsal supreme fascicles (X, Y, apex) arising from the IC and EC; pre\u2010commissurally, basal fascicles connecting the ventral part of the EC with the lateral zone of the ventral pallidum (VP) and, post\u2010commissurally, superior (Z<jats:sub>1<\/jats:sub>), middle (Z<jats:sub>2<\/jats:sub>) and lower (Z<jats:sub>3<\/jats:sub>) fascicles, connecting at different levels the EC with the GP. The results suggest that the presumptive cortical efferent and afferent fibres to the pallidum could be organized according to a dorsal to ventrolateral topography in the sheep, similar to that seen in other mammals. The proposed methodology has the potential to delineate the myeloarchitectonic patterns of nervous systems and tracts.<\/jats:p>","DOI":"10.1111\/ahe.12604","type":"journal-article","created":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T02:33:27Z","timestamp":1597372407000},"page":"84-92","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Connections between the internal and the external capsules and the globus pallidus in the sheep: A dichromate stain X\u2010ray microtomographic study"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3455-2378","authenticated-orcid":false,"given":"Jorge Alfonso","family":"Murillo\u2010Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Department of Anatomy and Embryology Faculty of Medicine Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belen","family":"Notario","sequence":"additional","affiliation":[{"name":"Microcomputed Tomography Lab Centro Nacional de Investigaci\u00f3n sobre la Evoluci\u00f3n Humana CENIEH Burgos Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estela","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology Faculty of Medicine Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Martinez\u2010Sanz","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology Faculty of Medicine Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Carmen","family":"Barrio","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology Faculty of Medicine Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Herrera","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Embryology Faculty of Medicine Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3134-07.2007"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901150304"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.24768"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.28.1.71"},{"key":"e_1_2_9_6_1","first-page":"7","article-title":"Anatomy of the basal ganglia and related nuclei: A review","volume":"14","author":"Carpenter M. B.","year":"1976","journal-title":"Advances in Neurology"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.29.5.426"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8617406"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2008.03.006"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780361019"},{"key":"e_1_2_9_11_1","unstructured":"Dejerine J.(1980).Anatomie des Centres Nerveux.Paris France:Masson SA."},{"key":"e_1_2_9_12_1","first-page":"20","article-title":"Soft tissue discrimination with contrast agents using micro\u2010CT scanning","volume":"144","author":"Descamps E.","year":"2014","journal-title":"Belgian Journal of Zoology"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.24079"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2015.09.001"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.22561"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000485476"},{"key":"e_1_2_9_17_1","first-page":"237","article-title":"Fiber connections of the basal ganglia","volume":"51","author":"Graybiel A. M.","year":"1975","journal-title":"Progress in Brain Research"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep20681"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(92)91679-9"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2016.05.012"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7483745"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.12871\/00039829201815"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00125"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007252"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq063"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90863-X"},{"key":"e_1_2_9_27_1","volume-title":"The Sheep Brain Atlas. Brain Biodiversity bank","author":"Johnson J. I.","year":"1998"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/92.3.477"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/93.3.525"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1971.0106"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.23225"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(77)90238-2"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980200047"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6793-9-11"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25995"},{"key":"e_1_2_9_36_1","first-page":"714e","article-title":"Secund\u00e4re Degenerationen nach Durchschneidung des Balkens","volume":"12","author":"Muratoff W.","year":"1893","journal-title":"Neurologisches Centralblatt"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2019.01.007"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)90397-2"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(79)90060-5"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)91385-6"},{"key":"e_1_2_9_41_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.17756\/jnen.2019-054","article-title":"Neurological examination of sheep (Ovis aries) with unilateral and bilateral quinolinic acid lesions of the striatum assessed by magnetic resonance imaging","volume":"5","author":"O\u2019Connell A.","year":"2019","journal-title":"Journal of Neurology and Experimental Neuroscience"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900690210"},{"key":"e_1_2_9_43_1","first-page":"21","article-title":"A summary of fiber connections of the basal ganglia with each other and with other portions of the brain","volume":"21","author":"Papez J. W.","year":"1941","journal-title":"Research publications, association for research in nervous and mental disease"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0173(94)00007-C"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmi.12013"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2017.199"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-0485-2_3"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1941.02280200036002"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.3233\/JHD-130067"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-381328-2.00014-6"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(82)90321-4"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02509542"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-16641-0_5"},{"key":"e_1_2_9_54_1","volume-title":"Atlas for stereotaxy of the human brain","author":"Schaltenbrand G.","year":"1977"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195104233.001.0001"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.179077"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(91)90176-T"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.4248\/IJOS09031"},{"key":"e_1_2_9_59_1","first-page":"91","article-title":"The external capsule in the dog\u2019s brain (myeloarchitectonics and topography)","volume":"20","author":"Sych L.","year":"1960","journal-title":"Acta Biologiae Experimentalis"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(81)90154-2"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.3233\/JHD-130053"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901990205"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-374767-9.00014-7"},{"key":"e_1_2_9_64_1","first-page":"532","article-title":"Cortico\u2010striate interrelations in the albino rat","volume":"95","author":"Webster K. E.","year":"1961","journal-title":"Journal of Anatomy"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/36.3-4.427"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr088"}],"container-title":["Anatomia, Histologia, Embryologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fahe.12604","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ahe.12604","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ahe.12604","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ahe.12604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T23:24:14Z","timestamp":1693697054000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ahe.12604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,13]]},"references-count":65,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/ahe.12604"],"URL":"https:\/\/doi.org\/10.1111\/ahe.12604","archive":["Portico"],"relation":{},"ISSN":["0340-2096","1439-0264"],"issn-type":[{"value":"0340-2096","type":"print"},{"value":"1439-0264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,13]]},"assertion":[{"value":"2020-03-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}