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Morphometric measurements (mm 100g fish<jats:sup>\u22121<\/jats:sup>) of the liver width and stomach length in rainbow trout were found to be significantly larger (<jats:italic>p<\/jats:italic> &lt;0.05) in fish with high\u2010level pea protein as the main protein source (PP75, PP100) compared to the low\u2010level PP replacement group (PP25). No significant differences were found in morphometric measurements for pyloric caecum and intestines among treatment groups, whereas the number of the caecum of fish fed the PP25 diets significantly increased over the control (PP0) (<jats:italic>p<\/jats:italic>&lt;0.05). In the histological examination of the liver, mild hydropic and vacuolar degeneration was observed in all experimental groups except PP0 and PP25. The measurements of pyloric caecum fold height, enterocyte length and width of tunica muscularis of the high\u2010level pea protein groups of PP75 and PP100 were significantly higher (<jats:italic>p<\/jats:italic> &lt;0.05) compared to the control group. In conclusion, 25% substitution of PP can be suggested for FM in trout diets, because the findings of the present study provided evidence that the digestive system improved by increasing the number of pyloric caecum at this replacement level.<\/jats:p>","DOI":"10.1111\/ahe.12740","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T23:12:53Z","timestamp":1632525173000},"page":"956-964","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Does dietary incorporation level of pea protein isolate influence the digestive system morphology in rainbow trout (<i>Oncorhynchus mykiss<\/i>)?"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7557-0452","authenticated-orcid":false,"given":"Beste","family":"Demirci","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Anatomy Kastamonu University Kastamonu Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6184-5408","authenticated-orcid":false,"given":"Funda","family":"Terzi","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Pathology Kastamonu University Kastamonu Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1576-1836","authenticated-orcid":false,"given":"Osman Sabri","family":"Kesbic","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Animal Nutrition and Nutritional Diseases Kastamonu University Kastamonu Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2515-5490","authenticated-orcid":false,"given":"Umit","family":"Acar","sequence":"additional","affiliation":[{"name":"Bayrami\u00e7 Vocational School Department of Forestry \u00c7anakkale Onsekiz Mart University \u00c7anakkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4809-5809","authenticated-orcid":false,"given":"Sevdan","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Marine Science and Technology Faculty Department of Aquaculture \u00c7anakkale Onsekiz Mart University \u00c7anakkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3942-5703","authenticated-orcid":false,"given":"Fevziye Isil","family":"Kesbic","sequence":"additional","affiliation":[{"name":"Central Research Laboratuvary Kastamonu University Kastamonu Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/are.13724"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2761.1996.d01-92.x"},{"key":"e_1_2_9_4_1","first-page":"57","volume-title":"Fish physiology","author":"Bakke A. 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