{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T12:56:44Z","timestamp":1788353804127,"version":"build-2803163510"},"reference-count":76,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T00:00:00Z","timestamp":1734134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010253","name":"Secretar\u00eda de Ciencia y T\u00e9cnica, Universidad de Buenos Aires","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010253","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The coypu (<jats:styled-content style=\"fixed-case\"><jats:italic>Myocastor coypus bonariensis<\/jats:italic><\/jats:styled-content>) is an annual polyestrous hystricomorph rodent with variable\u2010length oestrous cycles, which ovarian histoarchitecture during this period is not fully described. This study analyses variations in ovarian morphology during the oestrous cycle, focusing on follicular development and atresia. Eighteen sexually mature virgin females aged 7\u20139\u2009months, weighing 4.795\u2009\u00b1\u20090.3996\u2009kg, were used. Daily colpocytological analyses were performed to establish the cycle duration, followed by euthanasia at different phases\u2014prooestrus, estrus, meteostrus, and on days 5, 10, and 20 of dioestrus. Morphology and superficial appearance of the ovaries, weight, and volume at each stage were recorded, and volume increase over time was analysed. A morphological classification and size ranges every 100\u2009\u03bcm for follicular development analysis were used. Relative area analysis determined the proportions of different ovarian components and the absolute and relative frequencies of atretic and\/or luteinized structures. Our study revealed differences between prooestrus, meteostrus, and all dioestrus phases, as well as between oestrus and metoestrus, and dioestrus at 10 and 20\u2009days. Ovarian surface exhibited variations across different oestrous cycle stages, and atretic follicles were observed in all analysed stages. These findings provide new data and contribute to the understanding of the reproductive cycle in this species.<\/jats:p>","DOI":"10.1111\/ahe.70009","type":"journal-article","created":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T08:35:32Z","timestamp":1734165332000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Coypu (<i>Myocastor coypus bonaeriensis<\/i>) Ovarian Morphology During the Oestrous Cycle"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0044-7657","authenticated-orcid":false,"given":"Antonio Eduardo","family":"Felipe","sequence":"first","affiliation":[{"name":"Universidad Nacional del Centro de la Provincia de Buenos Aires, Facultad de Ciencias Veterinarias, Centro de Investigaciones Biol\u00f3gicas Laboratorio de Histolog\u00eda y Embriolog\u00eda  Tandil Buenos Aires Province Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1135-6243","authenticated-orcid":false,"given":"Juan Manuel","family":"Herrera","sequence":"additional","affiliation":[{"name":"Universidad Nacional del Centro de la Provincia de Buenos Aires, Facultad de Ciencias Veterinarias, Centro de Investigaciones Biol\u00f3gicas Laboratorio de Histolog\u00eda y Embriolog\u00eda  Tandil Buenos Aires Province Argentina"},{"name":"Centro de Investigaci\u00f3n Veterinaria de Tandil (CIVETAN) UNCPBA\u2010CICPBA\u2010CONICET  Tandil Buenos AIres Province Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Pablo","family":"Killian","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Ciencias Veterinarias C\u00e1tedra de Histolog\u00eda y Embriolog\u00eda  Buenos Aires Argentina"},{"name":"Universidad de Buenos Aires, Facultad de Ciencias Veterinarias Instituto de Investigaci\u00f3n y Tecnolog\u00eda en Reproducci\u00f3n Animal (INITRA)  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0677-7702","authenticated-orcid":false,"given":"Daniel Marcelo","family":"Lombardo","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Ciencias Veterinarias C\u00e1tedra de Histolog\u00eda y Embriolog\u00eda  Buenos Aires Argentina"},{"name":"Universidad de Buenos Aires, Facultad de Ciencias Veterinarias Instituto de Investigaci\u00f3n y Tecnolog\u00eda en Reproducci\u00f3n Animal (INITRA)  Buenos Aires Argentina"},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET)  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des297"},{"issue":"5","key":"e_1_2_8_3_1","article-title":"Comparative Characterization of the Oestrous Cycles of the Grasscutter (\n                     Thryonomys swinderianus\n                  ) and the Guinea Pig (\n                     Cavia porcellus\n                  ) by the Hystricomorph Vaginal Membrane Perforation Phenomenon","volume":"19","author":"Addo G.","year":"2007","journal-title":"Livestock Research for Rural Development"},{"issue":"4","key":"e_1_2_8_4_1","article-title":"Reproductive Characteristics of the Female Grasscutter (\n                     Thryonomys swinderianus\n                  ) and Formulation of Colony Breeding Strategies","volume":"19","author":"Addo G.","year":"2007","journal-title":"Livestock Research for Rural Development"},{"key":"e_1_2_8_5_1","first-page":"201","volume-title":"The Ovary","author":"Bowen\u2010Shauver J. 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