{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T23:45:52Z","timestamp":1761176752017,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    We studied sows (Landrace\u2009\u00d7\u2009Yorkshire line, DanBred Hybrid) to evaluate the possible changes in progesterone receptor (PR) expression in the uterus and ovary caused by different non\u2010hypophyseal gonadotropins treatments: equine chorionic gonadotropin (eCG) and human chorionic gonadotropin (hCG). Varying concentrations of eCG and hCG were evaluated (Groups 1, 2, 3, 4). PR expression was determined by immunohistochemistry, and labelling intensity was determined by the HScore method. In the ovary, PR expression in the granulosa cells of follicles did not differ significantly between Groups 1 and 2 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) but differed significantly from that in Groups 3 and 4 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), which in turn did not differ from each other. This PR expression pattern was similar across groups in the internal and external theca cells. Conversely, in the uterus, PR expression in the lining epithelium was lower in Group 4 than that in Group 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Increased expression was observed in the endometrial lamina propria in all groups 2 and 4 compared to that in the control group (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Decreased expression was observed in the glandular epithelium and myometrium in Group 4 compared to that in Group 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). In the ovary, PR expression in the granulosa and outer and inner theca of the follicles was not significantly different (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) between Groups 1 and 2 or Groups 3 and 4; however, the expression in these pairs of groups differed from each other. Thus, changes in PR expression may depend on the concentrations and proportions of exogenous hormones used in the treatments, indicating an alteration in the reproductive process.\n                  <\/jats:p>","DOI":"10.1111\/ahe.70017","type":"journal-article","created":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T00:54:33Z","timestamp":1738457673000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differential Expression\/Regulation of Progesterone Receptor in Reproductive Tissues (Ovary and Uterus) Induced by Human Chorionic Gonadotropin and Equine Chorionic Gonadotropin Treatments in Sows"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2210-5738","authenticated-orcid":false,"given":"Oswaldo Cruz","family":"Le\u00f3n","sequence":"first","affiliation":[{"name":"Morphology Department, Facultad de Medicina Veterinaria y Zootecnia National Autonomous University of Mexico  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago Ren\u00e9","family":"Anzald\u00faa Arce","sequence":"additional","affiliation":[{"name":"Morphology Department, Facultad de Medicina Veterinaria y Zootecnia National Autonomous University of Mexico  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Angel","family":"Cornejo Cortes","sequence":"additional","affiliation":[{"name":"Biological Sciences Department, Facultad de Estudios Superiores Cuautitl\u00e1n National Autonomous University of Mexico  Cuautitl\u00e1n Izcalli State of Mexico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Cerb\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Biology, Facultad de Qu\u00edmica National Autonomous University of Mexico  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Ernesto Mart\u00ednez","family":"Casta\u00f1eda","sequence":"additional","affiliation":[{"name":"Institute of Agriopecurial and Rural Sciences (ICAR) Campus \u201cEl Cerillo Piedras Blancas\u201d Toluca UAEM  Toluca State of Mexico Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ra\u00fal Ulloa","family":"Arvizu","sequence":"additional","affiliation":[{"name":"Genetics and Biostatistics Department, Facultad de Medicina Veterinaria y Zootecnia National Autonomous University of Mexico  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Elena","family":"Trujillo Ortega","sequence":"additional","affiliation":[{"name":"Pig's Medicine and Zootechnics Department, Facultad de Medicina Veterinaria y Zootecnia National Autonomous University of Mexico  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.ANIREPROSCI.2005.12.007"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093\u2010691X(03)00257\u20107"},{"key":"e_1_2_9_4_1","first-page":"19","article-title":"Regulation and Action of Gonadotrophinsin Pigs","volume":"40","author":"Esbenshade K. 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L.","key":"e_1_2_9_11_1"},{"key":"e_1_2_9_12_1","first-page":"43","article-title":"Steroid Receptors and Their Roles in Pig Uterus","volume":"41","author":"Srisuwatanasagul S.","year":"2011","journal-title":"Thai Journal of Veterinary Medicine"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2016.07.002"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12433"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2016.06.027"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2018.04.001"}],"container-title":["Anatomia, Histologia, Embryologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ahe.70017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:32:06Z","timestamp":1761129126000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ahe.70017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/ahe.70017"],"URL":"https:\/\/doi.org\/10.1111\/ahe.70017","archive":["Portico"],"relation":{},"ISSN":["0340-2096","1439-0264"],"issn-type":[{"type":"print","value":"0340-2096"},{"type":"electronic","value":"1439-0264"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70017"}}