{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T05:44:05Z","timestamp":1782711845827,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Among domestic animals, pigs serve as valuable biomodels for studying endocrine disorders due to similarities in the structure and hormone production of their pituitary gland with humans. The pituitary gland is a central regulator of hormonal balance and plays a crucial role in various physiological functions. The present ultrastructural studies of the porcine pituitary gland not only enhance our understanding of porcine anatomy but also provide valuable comparative data for understanding the functioning of the human pituitary gland. The pituitary gland of the pig consisted of adenohypophysis and neurohypophysis. The adenohypophysis was differentiated into pars distalis, pars intermedia, and pars tuberalis, while the neurohypophysis was divided into median eminence, infundibular stalk, and pars nervosa. Each lobe had a wide variety of hormone\u2010secreting cells. The somatotrophs contained numerous electron\u2010dense round secretory granules and rough endoplasmic reticula. The lactotrophs contained large electron\u2010dense secretory granules in different shapes. The thyrotrophs contained smaller secretory granules with few mitochondria and Golgi complex. The gonadotrophs contained round electron\u2010dense to electron\u2010lucid secretory granules. The corticotrophs contained numerous round to oval\u2010shaped electron\u2010dense secretory granules and more of Golgi complex and mitochondria. In pars intermedia, granular cells, non\u2010granular cells, elongated cells, interstitial cells, and the cleft lining cells with microvilli were noticed, whereas in the pars tuberalis, granulated cells, non\u2010granulated cells and interstitial cells were observed. In the pars nervosa, numerous bundles of non\u2010myelinated axons and few myelinated axons along with pituicytes were noticed. The axon terminals contained electron\u2010dense to electron\u2010lucid Herring bodies and numerous mitochondria.<\/jats:p>","DOI":"10.1111\/ahe.70098","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:10:26Z","timestamp":1772989826000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrastructural Studies on the Pituitary Gland of Pig (\n                    <i>Sus scrofa domestica<\/i>\n                    )"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0202-6465","authenticated-orcid":false,"given":"Harideep","family":"Vaka","sequence":"first","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary and Animal Sciences  Mannuthy Kerala India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santhi Lakshmi","family":"Mukku","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagapathi Ramayya","family":"Palla","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharathi","family":"Seelam","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Complex College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reddy Dhyana","family":"Vaka","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. S.","family":"Chandrasekhara Rao","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7760-9816","authenticated-orcid":false,"given":"Supriya","family":"Botlagunta","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4221-5558","authenticated-orcid":false,"given":"Raja","family":"Kannekati","sequence":"additional","affiliation":[{"name":"Department of Veterinary Anatomy College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kalyan Chakravarthi","sequence":"additional","affiliation":[{"name":"Indian Council of Agricultural Research\u2010All India Co\u2010Ordinated Research Project on Pigs (ICAR\u2010AICRP on Pigs) College of Veterinary Science  Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00666218"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1201\/b15184"},{"key":"e_1_2_9_4_1","volume-title":"Textbook of Applied Veterinary Histology","author":"Banks W. 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E.","year":"1984"},{"key":"e_1_2_9_14_1","first-page":"9","article-title":"Follicular Structures in the Hypophysis of Pigs","volume":"98","author":"Kubo M.","year":"1992","journal-title":"Bulletin NIAH, Ibarki, Japan"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(61)90007-7"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.25.3.179"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.3.179"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2307\/1292491"},{"key":"e_1_2_9_19_1","first-page":"39","article-title":"Morpho\u2010Histology of Pituitary Gland of Non Descript Male Goats (Capra hircus)","volume":"6","author":"Nagamalleswari Y.","year":"1994","journal-title":"Indian Journal of Veterinary Anatomy"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.21608\/jcvr.2021.199414"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1679\/aohc1950.27.501"},{"key":"e_1_2_9_22_1","unstructured":"Paramasivan S.2007.\u201cGross Anatomical and Histo Morphological Studies on Hypo Thalamo\u2010Hypo Physio\u2010Mammary Axis of Sheep (Ovis aries).\u201d Ph.D. Thesis Tamil Nadu Veterinary and Animal Sciences University."},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00233839"},{"key":"e_1_2_9_24_1","first-page":"132","article-title":"Histological Study of Hypophysis Cerebri in Buffaloes (Bubalus bubalis)","volume":"33","author":"Raja K.","year":"2021","journal-title":"Indian Journal of Veterinary Anatomy"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/1.2.93"},{"key":"e_1_2_9_26_1","unstructured":"Sharma A.2019.\u201cGross Morphological Histological and Histochemical Studies on Pineal Pituitary Thyroid and Adrenal Glands of Jaffarabadi Buffalo During Different Seasons of the Year.\u201d Ph.D Thesis Junagadh Agricultural University."},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00222341"},{"key":"e_1_2_9_28_1","unstructured":"Singh G.1982.\u201cHistomorphology and Histochemistry of the Pituitary Gland During Different Stages of Pregnancy in Sheep.\u201d MVSc Thesis Lajpat Rai University of Veterinary and Animal Sciences."},{"key":"e_1_2_9_29_1","unstructured":"Trautmann A. andJ.Fiebiger.1952.\u201cFundamentals of the Histology of Domestic Animals.\u201d"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.2220\/biomedres.9.1"}],"container-title":["Anatomia, Histologia, Embryologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ahe.70098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ahe.70098","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ahe.70098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T04:51:34Z","timestamp":1782708694000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ahe.70098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/ahe.70098"],"URL":"https:\/\/doi.org\/10.1111\/ahe.70098","archive":["Portico"],"relation":{},"ISSN":["0340-2096","1439-0264"],"issn-type":[{"value":"0340-2096","type":"print"},{"value":"1439-0264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2026-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70098"}}