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Here, the \u2018Thrifty Genotype\u2019 hypothesis and the evolutionary background of Pacific populations are examined. We question its relevance not only in the Pacific region but more generally. Not only has the hypothesis not been explicitly tested, but most archaeological and anthropological data from the Pacific fundamentally do not support its application.<\/jats:p>","DOI":"10.1111\/ahg.12132","type":"journal-article","created":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T04:05:57Z","timestamp":1443585957000},"page":"470-480","source":"Crossref","is-referenced-by-count":50,"title":["Pacific Populations, Metabolic Disease and \u2018Just\u2010So Stories\u2019: A Critique of the \u2018Thrifty Genotype\u2019 Hypothesis in Oceania"],"prefix":"10.1111","volume":"79","author":[{"given":"Anna L.","family":"Gosling","sequence":"first","affiliation":[{"name":"Department of Biochemistry University of Otago Dunedin New Zealand"},{"name":"Department of Anatomy University of Otago Dunedin New Zealand"},{"name":"Allan Wilson Centre for Molecular Ecology and Evolution University of Otago Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hallie R.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Department of Anatomy University of Otago Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Matisoo\u2010Smith","sequence":"additional","affiliation":[{"name":"Department of Anatomy University of Otago Dunedin New Zealand"},{"name":"Allan Wilson Centre for Molecular Ecology and Evolution University of Otago Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony R.","family":"Merriman","sequence":"additional","affiliation":[{"name":"Department of Biochemistry University of Otago Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2008.558"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.35.5.353"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/204566"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.12.010"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0003598X00094448"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/scin.2014.186006019"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20334"},{"key":"e_1_2_5_9_1","first-page":"1111","article-title":"Genetic signatures of strong recent positive selection at the lactase gene","volume":"74","author":"Bersaglieri T.","year":"2004","journal-title":"Am J Med Genet"},{"key":"e_1_2_5_10_1","first-page":"83","article-title":"Notes on the custom of Rahui: Its application and manipulation, as also its supposed powers, its rites, invocations and superstitions","volume":"13","author":"Best E.","year":"1904","journal-title":"J Polyn Soc"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8644(199710)104:2<201::AID-AJPA6>3.0.CO;2-0"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8644(200012)113:4<481::AID-AJPA4>3.0.CO;2-1"},{"key":"e_1_2_5_13_1","volume-title":"Bioarchaeology of Southeast Asia (","author":"Buckley H. 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