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Molecular analysis was performed using PCR\u2010RFLP and allele\u2010specific PCR. Data were analysed using descriptive statistics, tests of independence, and regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Frequencies of 3.1%, 2.2%, 72.2%, 2.1%, 2.8%, and 11% were found for the resistance alleles HbS, HbC, Duffy, \u03b2\u2010thalassemia\u201029, \u03b2\u2010thalassemia\u201088 and G6PD, respectively. In addition, adolescents and young adults (13 to 26 years) presented the highest proportion of resistance genotypes. Likewise, the communities of the insular zone of Buenaventura had the highest proportion of resistance genotypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings should be considered by public health and disease prevention authorities, as they highlight specific age groups and communities that may be more susceptible to malaria infection. They also identify groups that may contribute to the persistence and potential increase in the prevalence of haemoglobinopathies in the population over time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ahg.70022","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T04:49:58Z","timestamp":1756356598000},"page":"99-112","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of the Main Human Genetic Variants Related to Resistance to Malaria in a Population of the Colombian Pacific Coast"],"prefix":"10.1111","volume":"90","author":[{"given":"Diana Carolina","family":"Ortega","sequence":"first","affiliation":[{"name":"Human Molecular Genetics Group, Department of Biology Universidad del Valle  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Paula","family":"Arango","sequence":"additional","affiliation":[{"name":"Human Molecular Genetics Group, Department of Biology Universidad del Valle  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Ca\u00f1\u00f3n","sequence":"additional","affiliation":[{"name":"Human Molecular Genetics Group, Department of Biology Universidad del Valle  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heiber","family":"C\u00e1rdenas","sequence":"additional","affiliation":[{"name":"Human Molecular Genetics Group, Department of Biology Universidad del Valle  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranulfo","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Entomological Research Group, Department of Biology Universidad del Valle  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Barreto","sequence":"additional","affiliation":[{"name":"Human Molecular Genetics Group, Department of Biology Universidad del Valle  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010019\u20102918\u20104"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.32641\/rchped.vi91i4.1438"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.25100\/cm.v43i3.925"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0257562"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2012.013"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00034989859366"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.25100\/cm.v41i.2.695"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.v15i1.850"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1596\/978-1-4648-0423-6_ch14"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010021\u201003618\u20100"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1415\u2010790x2008000200007"},{"key":"e_1_2_11_13_1","unstructured":"CDC\u2014Centers for Disease Control and Prevention.2009.CDC\u2014Malaria\u2014Malaria Worldwide\u2014Impact of Malaria.https:\/\/www.cdc.gov\/malaria\/malaria_worldwide\/impact.html."},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.15085"},{"key":"e_1_2_11_15_1","unstructured":"DANE.2020.La Informaci\u00f3n del DANE en la Toma de Decisiones de Los Municipios Del Pa\u00eds. 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