{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T14:02:12Z","timestamp":1789135332282,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T00:00:00Z","timestamp":1511222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["K01 DA030446"],"award-info":[{"award-number":["K01 DA030446"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01 DA016759"],"award-info":[{"award-number":["R01 DA016759"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Addict"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>While research on the separate relationships between health\u2010related quality of life (HRQOL) and chronic pain, and HRQOL and opioid abuse has been sparse, even less work has investigated the factors associated with HRQOL in individuals who have both chronic pain and meet criteria for opioid use disorder. The data presented in this analysis should allow a better understanding the factors important to quality of life among this dual\u2010diagnosed population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Individuals with dual diagnoses of chronic pain and opioid use disorder were recruited for clinical research studies at Columbia University Medical Center. Participants (<jats:italic>n<\/jats:italic>\u2009=\u200947) completed inventories to assess pain (Brief Pain Inventory), opioid (ab)use, and depression (Beck Depression Inventory). Variable from these and other inventories, along with demographic factors (age, race, sex, pain severity, depressive symptoms, duration of opioid use, route of opioid use, amount of opioid use) were entered into a regression analysis in order to identify the strongest predictors of SF\u201036 Health Survey score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the bivariate analysis we found that demographic and drug use variables were rarely associated with HRQOL. Typically, ratings of pain severity and pain interference were the best predictors. In the multivariate analysis, we found that across the several HRQOL dimensions greater Brief Pain Inventory (BPI) ratings of pain \u201cinterference\u201d and Beck Depression Inventory (BDI) scores were consistently associated with lower HRQOL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Scientific Significance<\/jats:title><jats:p>These data suggest that insufficient pain management and depression are significant variables contributing to lower quality of life among individuals with chronic pain and opioid use disorder. (Am J Addict 2017;26:815\u2013821)<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajad.12637","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T12:16:36Z","timestamp":1511266596000},"page":"815-821","source":"Crossref","is-referenced-by-count":27,"title":["Chronic pain and opioid abuse: Factors associated with health\u2010related quality of life"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4476-2800","authenticated-orcid":false,"given":"Jermaine D.","family":"Jones","sequence":"first","affiliation":[{"name":"Division on Substance Use Disorders, New York State Psychiatric Institute and Department of Psychiatry College of Physicians and Surgeons of Columbia University New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan S.","family":"Vogelman","sequence":"additional","affiliation":[{"name":"Division on Substance Use Disorders, New York State Psychiatric Institute and Department of Psychiatry College of Physicians and Surgeons of Columbia University New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Luba","sequence":"additional","affiliation":[{"name":"Division on Substance Use Disorders, New York State Psychiatric Institute and Department of Psychiatry College of Physicians and Surgeons of Columbia University New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mudassir","family":"Mumtaz","sequence":"additional","affiliation":[{"name":"Division on Substance Use Disorders, New York State Psychiatric Institute and Department of Psychiatry College of Physicians and Surgeons of Columbia University New York New York"},{"name":"Translational Research Training Program in Addiction City College of New York New York"},{"name":"Sophie Davis School of Biomedical Education New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra D.","family":"Comer","sequence":"additional","affiliation":[{"name":"Division on Substance Use Disorders, New York State Psychiatric Institute and Department of Psychiatry College of Physicians and Surgeons of Columbia University New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/10550887.2011.581961"},{"key":"e_1_2_8_3_1","volume-title":"Relieving Pain in America, A Blueprint for Transforming Prevention, Care, Education and Research","year":"2011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(97)00126-7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2010.01.010"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(02)00411-6"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826080500260800"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023585707046"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-004-3062-2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2003.11.003"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2004.04.005"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1747-597X-3-2"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000110409"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000090426"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/16066350801911948"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2003.03040.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1533-2500.2001.01016.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.06.009"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.133.4.581"},{"key":"e_1_2_8_20_1","unstructured":"Drug Enforcement Administration (2013) Heroin Domestic Monitor Program. 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