{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:12:48Z","timestamp":1791421968617,"version":"4.3.3"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["K24DA022412"],"award-info":[{"award-number":["K24DA022412"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Addict"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>We examined age differences across genders in clinical characteristics in emerging adult (\u226425 years) vs older adult patients (26+ years) with opioid use disorder (OUD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants (N\u2009=\u2009570; 30% female) entering a comparative effectiveness medication trial of buprenorphine vs extended\u2010release naltrexone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Differences in clinical characteristics in emerging adult vs older participants were similar across genders. However, women 26+ years reported more mental health problems compared with women \u226425, while men \u226425 years reported more mental health problems compared with men 26+ years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusion<\/jats:title><jats:p>Different strategies for emerging adult and older patients seeking OUD treatment may be necessary to address psychiatric comorbidities that differ across genders in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Scientific Significance<\/jats:title><jats:p>Comprehensive psychiatric assessment should be systematically included in OUD treatment for all genders. Treatment should focus on the emerging adult developmental phase when appropriate, with psychiatric treatment tailored for women and men, separately, across the lifespan. (Am J Addict 2020;29:536\u2013542)<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajad.13059","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T22:04:11Z","timestamp":1590098651000},"page":"536-542","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Substance Use and Mental Health in Emerging Adult Vs Older Adult Men and Women With Opioid Use Disorder"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5576-4150","authenticated-orcid":false,"given":"Celestina","family":"Barbosa\u2010Leiker","sequence":"first","affiliation":[{"name":"College of Nursing Washington State University Spokane Washington"},{"name":"Program of Excellence in Addictions Research Washington State University Spokane Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4247-9980","authenticated-orcid":false,"given":"Aimee N.C.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Columbia University Irving Medical Center and New York State Psychiatric Institute New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Pavlicova","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Columbia University Mailman School of Public Health New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Scodes","sequence":"additional","affiliation":[{"name":"Division of Mental Health Data Science New York State Psychiatric Institute New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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