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Existing evidence suggests that dream recollection may be influenced by clinically relevant phenomena, such as opioid use and withdrawal, general sleep disturbance, affective symptoms, and chronic pain. However, very few studies have explored drug\u2010related dreams among individuals who screened positive for opioid use disorder (OUD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adults recruited from Amazon Mechanical Turk (MTurk) who screened positive for OUD (<jats:italic>N\u2009<\/jats:italic>=\u2009154) completed a questionnaire about drug\u2010related dreams, as well as measures assessing sleep, opioid use history, stress, anxiety, and chronic pain. <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> analyses, one\u2010way analysis of variance, and bivariate correlations, correcting for the false discovery rate, were used as appropriate to explore correlates of (1) recollecting a drug\u2010related dream, and (2) experiencing post\u2010dream craving and distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Individuals who recollected a past\u2010week drug\u2010related dream were more likely to report other recent sleep disturbances, including poorer sleep quality, greater insomnia symptoms, and a higher risk for sleep apnea. Post\u2010dream craving and distress were both associated with greater insomnia symptoms, poor sleep hygiene behaviors, and greater anxiety symptoms. Individuals who had ever experienced a drug\u2010related dream (recently, or in their lifetime) were more likely to report a history of severe withdrawal, overdose, and intravenous opioid use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and Scientific Significance<\/jats:title><jats:p>Drug\u2010related dreams were common among individuals in the present sample and were related to other clinically relevant phenomena. Interventions that treat co\u2010occurring OUD, pain, sleep symptoms, and affective symptoms may improve overall well\u2010being in this population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajad.13219","type":"journal-article","created":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T02:19:06Z","timestamp":1630289946000},"page":"37-45","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinical correlates of drug\u2010related dreams in opioid use disorder"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8156-6772","authenticated-orcid":false,"given":"Jennifer D.","family":"Ellis","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jami 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