{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:56:51Z","timestamp":1791619011648,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Addict"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Patients increasingly rely on the Internet for healthcare information. This study aimed to evaluate the quality of videos on 3,4\u2010methylenedioxymethamphetamine (MDMA)\u2010assisted psychotherapy for posttraumatic stress disorder (PTSD) on YouTube\u2122.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>YouTube\u2122 was searched for the terms \u201cMDMA\u201d and \u201cPTSD.\u201d The 100 most viewed videos were analyzed using three standard quality measures: Global Quality Scores (GQS), JAMA benchmark, and DISCERN. Viewer engagement features and source of upload, video duration, inclusion of patient narrative and\/or MD\/DO\/PhD, the mention of lack of Food and Drug Administration\u00a0(FDA) approval, side effects, potential for abuse, and use in conjunction with psychotherapy were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The videos were of poor quality (mean GQS: 2.26\u2009\u00b1\u20090.94\/5, JAMA: 1.96\u2009\u00b1\u20090.45\/4, and DISCERN: 29.5\u2009\u00b1\u20098.2\/80). A significant positive association was found between video quality and duration (GQS: <jats:italic>r<\/jats:italic>\u2009=\u2009.5857,\u00a0<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0001, JAMA: <jats:italic>r<\/jats:italic>\u2009=\u2009.279,\u00a0<jats:italic>p<\/jats:italic>\u2009=\u2009.0409, DISCERN: <jats:italic>r<\/jats:italic>\u2009=\u2009.5783,\u00a0<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0001). Videos including an MD\/DO\/PhD had the highest scores (GQS: 2.87\/5 [1.22],\u00a0<jats:italic>p<\/jats:italic>\u2009=\u2009.006, DISCERN: 38.35\/80 [13.32],\u00a0<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0003). A minority of videos were uploaded by academic institutions (1%); most were from professional organizations (29%). No correlation was found between quality and viewer engagement features\u2010number of views, subscribers, likes\/dislikes, or comments. A majority mentioned that MDMA must be used in conjunction with psychotherapy (85%) and is not FDA\u2010approved (82%) for PTSD. Only 32% of videos mentioned risks or potential for abuse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings highlight the need for better quality of online health material and an opportunity for involvement of healthcare professionals in the dissemination of accurate health information via content creation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Scientific Significance<\/jats:title><jats:p>This is the first study to examine publicly available information on the use of MDMA for PTSD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajad.13325","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T07:44:57Z","timestamp":1661327097000},"page":"502-507","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Assessing the quality of publicly available videos on MDMA\u2010assisted psychotherapy for PTSD"],"prefix":"10.1111","volume":"31","author":[{"given":"Mariam","family":"Kyarunts","sequence":"first","affiliation":[{"name":"Mayo Clinic Alix School of Medicine Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghna P.","family":"Mansukhani","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa L.","family":"Loukianova","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6627-2410","authenticated-orcid":false,"given":"Bhanu P.","family":"Kolla","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,24]]},"reference":[{"issue":"5","key":"e_1_2_8_2_1","first-page":"4","article-title":"Posttraumatic stress disorder: the burden to the individual and to society","volume":"61","author":"Kessler RC","year":"2000","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_8_3_1","first-page":"1","article-title":"PTSD and death from suicide","volume":"28","author":"Jaimie L","year":"2017","journal-title":"PTSD Res Q"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","unstructured":"GasparyanA NavarroD NavarreteF ManzanaresJ.Pharmacological strategies for post\u2010traumatic stress disorder (PTSD): from animal to clinical studies.Neuropharmacol.2022:109211.","DOI":"10.1016\/j.neuropharm.2022.109211"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01336-3"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0033354919874074"},{"key":"e_1_2_8_7_1","unstructured":"Health Online 2013;2013.https:\/\/www.pewresearch.org\/internet\/2013\/01\/15\/health-online-2013\/"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.9370"},{"key":"e_1_2_8_9_1","unstructured":"Alexa\u2010An Amazon.com Company. 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