{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:51:23Z","timestamp":1792734683787,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008944","name":"Iowa Department of Public Health","doi-asserted-by":"publisher","award":["5883AP45"],"award-info":[{"award-number":["5883AP45"]}],"id":[{"id":"10.13039\/100008944","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Addict"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Injection drug use is a driver of hepatitis C virus (HCV) transmission, thus integrating HCV care into addiction care is likely necessary for HCV elimination. Here we describe how we integrated HCV care into our addiction medicine (AM) clinic and evaluate its effect on HCV treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Integrated care involves HCV screening and treatment with either DAA prescription directly in AM clinic or via telemedicine with an infectious diseases (ID) specialist. Using retrospective chart review, we assessed if the program affected rates of direct\u2010acting antivirals (DAA) initiation, DAA completion, and sustained virological response (SVR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 72 treatment na\u00efve patients, the rate of DAA initiation increased after integrated care (HR 2.21, 95% CI 1.05\u20134.66), but rates of DAA completion or SVR did not significantly increase. Integrated care was associated with more DAA prescriptions (0.6 vs. 0 prescriptions per month,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.004) and decreased referrals to hepatology (0.2 vs. 1 referrals per month,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.001). Compared to referring patients to hepatology, prescribing DAAs in AM clinic was associated with higher rates of DAA initiation (HR 42.46; 95% CI: 15.25\u2013118.24) and completion (HR 8.33; 95% CI: 2.76\u201325.16).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and Conclusions<\/jats:title>\n                    <jats:p>An integrated care program that involved both in\u2010person and telemedicine options improve access to DAA therapy. Enhancing interprofessional collaboration and expanding telemedicine services offers a practical model for strengthening HCV care delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Scientific Significance<\/jats:title>\n                    <jats:p>This study demonstrates a practical approach to integrating HCV care into addiction treatment through development of inter\u2010professional collaboration between healthcare specialties.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajad.70155","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:35:17Z","timestamp":1773336917000},"page":"534-542","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Improving access to direct acting antivirals via a multimodal integrated care program in an\u00a0addiction medicine clinic"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8031-8067","authenticated-orcid":false,"given":"Arya","family":"Zandvakili","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Rattenni","sequence":"additional","affiliation":[{"name":"Department of Family Medicine University of Iowa Carver College of Medicine Iowa City Iowa USA"},{"name":"Department of Psychiatry University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Burton","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi","family":"Guduguntla","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Osman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayeh","family":"Sabbagh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Arndt","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Iowa Carver College of Medicine Iowa City Iowa USA"},{"name":"Department of Biostatistics University of Iowa College of Public Health Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Miskle","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanhathai","family":"Kaewpoowat","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ohl","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Family Medicine University of Iowa Carver College of Medicine Iowa City Iowa USA"},{"name":"Department of Psychiatry University of Iowa Carver College of Medicine Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000927"},{"key":"e_1_2_8_3_1","unstructured":"Viral Hepatitis Surveillance Report \u2013 United States 2022. 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