{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:01:02Z","timestamp":1781668862756,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Addict"],"published-print":{"date-parts":[[2026,7]]},"abstract":"Abstract<\/jats:title>\n \n Background and Objectives<\/jats:title>\n Opioid use has been linked to increased stroke incidence and severity; however, data on effects during acute stroke hospitalization are limited.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We used the 2016\u20132020 National Inpatient Sample to evaluate the effects of opioid disorders on patient\u2010directed discharge (PDD) and length of stay (LOS) in 3,101,545 patients.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n On multivariate analysis, opioid disorders were independently associated with discharge AMA (aOR: 2.29; 95% CI: 1.98\u20132.65) and longer LOS (\u03b2: 1.5, SE: 0.138;\n p<\/jats:italic>\n \u2009<\u2009.001).\n <\/jats:p>\n <\/jats:sec>\n \n Discussion and Conclusions<\/jats:title>\n Opioid disorders may predispose PDD and prolonged hospital courses in stroke admissions.<\/jats:p>\n <\/jats:sec>\n \n Scientific Significance<\/jats:title>\n Opioid disorders may warrant targeted inpatient management and health system planning in stroke.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ajad.70157","type":"journal-article","created":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T09:15:39Z","timestamp":1774775739000},"page":"547-550","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Brief Report: Opioid\u2010related disorders increase patient\u2010directed discharge in admissions for hemorrhagic or ischemic stroke"],"prefix":"10.1111","volume":"35","author":[{"given":"Rohan M.","family":"Shah","sequence":"first","affiliation":[{"name":"Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4551-9266","authenticated-orcid":false,"given":"Shiv","family":"Patel","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent","family":"Schnipke","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Hamm","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000558"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2019.01041"},{"key":"e_1_2_7_4_1","unstructured":"Substance Abuse and Mental Health Services Administration.2022 NSDUH Annual National Report. Rockville MD: SAMHSA. 2022. Accessed April 10 2025.https:\/\/www.samhsa.gov\/data\/report\/2022-nsduh-annual-national-report"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000046"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2020.04.025"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-020-06366-0"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.21288"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)33078-2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M22-3049"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2024.3422"}],"container-title":["The American Journal on Addictions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajad.70157","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajad.70157","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajad.70157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:46:03Z","timestamp":1781667963000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajad.70157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,29]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/ajad.70157"],"URL":"https:\/\/doi.org\/10.1111\/ajad.70157","archive":["Portico"],"relation":{},"ISSN":["1055-0496","1521-0391"],"issn-type":[{"value":"1055-0496","type":"print"},{"value":"1521-0391","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,29]]},"assertion":[{"value":"2025-08-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}