{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:06:10Z","timestamp":1783937170619,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australas J Ageing"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to investigate the relationship between sarcopenia and frailty and examine factors associated with frailty among older patients with and without sarcopenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study was conducted on older inpatients and outpatients in Vietnam. Participants aged 60\u2009years or older were consecutively enrolled in the study. Sarcopenia was defined using the Asian Working Group for Sarcopenia (AWGS) 2019 criteria. Fried's frailty phenotype was applied to define frailty. Logistic regression models with frailty as the dependent variable were applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 835 patients (mean age: 71.3\u2009years, SD 8.4) were recruited. The overall prevalence of frailty was 17%. Among participants with and without frailty, 92% and 47% had sarcopenia, respectively. In unadjusted analysis, sarcopenia was significantly associated with increased frailty (OR 12.3, 95% CI 6.7\u201322.6) and remained significant after adjustment for sociodemographic factors (OR 6.3, 95% CI: 3.0\u201312.6) and for both sociodemographic and clinical factors (OR 5.4, 95% CI: 2.4\u201312.2). Among participants with sarcopenia, older age, inpatient status, having a high risk for falls, malnutrition and a history of hospitalisation in the last year were significantly associated with frailty. Among participants without sarcopenia, the factors associated with frailty were older age, inpatient status, low educational level, high risk of falls and malnutrition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study results highlighted that sarcopenia and frailty are two related but distinct geriatric syndromes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajag.13253","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T04:21:02Z","timestamp":1697430062000},"page":"281-287","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Factors associated with frailty in geriatric patients with and without sarcopenia in Vietnam"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9265-1887","authenticated-orcid":false,"given":"Tam Ngoc","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Geriatrics Hanoi Medical University  Hanoi Vietnam"},{"name":"Scientific Research Department National Geriatric Hospital  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8836-8920","authenticated-orcid":false,"given":"Tu Ngoc","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health, Westmead Applied Research Centre, Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5287-7483","authenticated-orcid":false,"given":"Janani","family":"Thillainadesan","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine and Centre for Education and Research on Ageing (CERA) Concord Hospital  Sydney New South Wales Australia"},{"name":"Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anh Trung","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Hanoi Medical University  Hanoi Vietnam"},{"name":"Scientific Research Department National Geriatric Hospital  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huong Thi Thu","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Hanoi Medical University  Hanoi Vietnam"},{"name":"Scientific Research Department National Geriatric Hospital  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thu Thi Hoai","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Hanoi Medical University  Hanoi Vietnam"},{"name":"Scientific Research Department National Geriatric Hospital  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huong Thi Thanh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Dinh Tien Hoang Institute of Medicine  Hanoi Vietnam"},{"name":"Physiology Department Hanoi Medical University  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh Xuan","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Hanoi Medical University  Hanoi Vietnam"},{"name":"Scientific Research Department National Geriatric Hospital  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7243-0796","authenticated-orcid":false,"given":"Vasi","family":"Naganathan","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine and Centre for Education and Research on Ageing (CERA) Concord Hospital  Sydney New South Wales Australia"},{"name":"Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3132-3801","authenticated-orcid":false,"given":"Huyen Thi Thanh","family":"Vu","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Hanoi Medical University  Hanoi Vietnam"},{"name":"Scientific Research Department National Geriatric Hospital  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12783"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-017-0609-y"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afaa219"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2017.04.018"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mlc.2001.113504"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31138-9"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2020.11.009"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14314"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2017.09.014"},{"key":"e_1_2_10_12_1","unstructured":"World Health Organization.Ageing and health.2022. Accessed April 2 2023.https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/ageing\u2010and\u2010health"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2009.02591.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-009-0214-7"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.NAJ.0000314810.46029.74"},{"issue":"1","key":"e_1_2_10_16_1","first-page":"93","article-title":"Katz index of independence in activities of daily living (ADL)","volume":"27","author":"Wallace M","year":"2007","journal-title":"Urol Nurs"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00255"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2023.01.023"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13072316"},{"key":"e_1_2_10_21_1","doi-asserted-by":"crossref","unstructured":"HoogendijkEO vanHoutHP HeymansMW et\u00a0al.Explaining the association between educational level and frailty in older adults: results from a 13\u2010year longitudinal study in the Netherlands.2014;24(7):538\u2010544.e2.","DOI":"10.1016\/j.annepidem.2014.05.002"}],"container-title":["Australasian Journal on Ageing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajag.13253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T04:37:28Z","timestamp":1758083848000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajag.13253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,16]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/ajag.13253"],"URL":"https:\/\/doi.org\/10.1111\/ajag.13253","archive":["Portico"],"relation":{},"ISSN":["1440-6381","1741-6612"],"issn-type":[{"value":"1440-6381","type":"print"},{"value":"1741-6612","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,16]]},"assertion":[{"value":"2022-11-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}