{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T11:29:45Z","timestamp":1781263785828,"version":"3.54.1"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018425","name":"Department for Innovation and Skills, Government of South Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018425","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009727","name":"Hospital Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009727","name":"Hospital Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australas J Ageing"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the co\u2010prescribing of analgesic and\/or adjuvant medications among residents of Australian and Finnish residential care homes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Secondary cross\u2010sectional analyses of prescribing data from residents of 12 Australian residential care homes in 2019 and 53 Finnish nursing homes and assisted living facilities in 2017\u20132018. Demographic characteristics and medication data were extracted from medical records and medication administration charts. Co\u2010prescribing was defined as more than one analgesic (acetaminophen, non\u2010steroidal anti\u2010inflammatory drugs and opioids) and\/or adjuvant (gabapentinoids, tricyclic antidepressants and duloxetine) medication prescribed for regular administration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 550 Australian residents (89 [IQR 84\u201392] years; 73% females) and 2423 Finnish residents (84 [IQR 65\u2013103] years; 74% females) were included. Of 416 Australian residents prescribed any regular analgesic or adjuvant, 181 (44%) were prescribed two or more, including 66 (16%) who were prescribed three or more. Of 1406 Finnish residents prescribed any regular analgesic or adjuvant, 469 (33%) were prescribed two or more, including 87 (6%) who were prescribed three or more. Acetaminophen was co\u2010prescribed to more than 75% of Australian and 43% of Finnish residents prescribed other analgesics or adjuvants. Of 61 Australian residents and 186 Finnish residents prescribed gabapentinoids, 38 (62%) and 86 (46%) were co\u2010prescribed opioids. Opioids were co\u2010prescribed to 59%\u201383% of Australian and 25%\u201346% of Finnish residents prescribed adjuvants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Analgesic and adjuvant co\u2010prescribing was more prevalent for Australian than Finnish residents, which was largely driven by acetaminophen co\u2010prescribing to more than three quarters of analgesic or adjuvant users in Australia. Central nervous system\u2010active polypharmacy arising from high rates of adjuvant and opioid co\u2010prescribing warrants further attention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajag.70062","type":"journal-article","created":{"date-parts":[[2025,7,13]],"date-time":"2025-07-13T12:07:43Z","timestamp":1752408463000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Analgesic and adjuvant co\u2010prescribing in Australian and\u00a0Finnish residential care homes"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2228-5508","authenticated-orcid":false,"given":"Laura A.","family":"Dowd","sequence":"first","affiliation":[{"name":"Centre for Medicine Use and Safety (CMUS), Faculty of Pharmacy and Pharmaceutical Sciences Monash University  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaisu H.","family":"Pitk\u00e4l\u00e4","sequence":"additional","affiliation":[{"name":"Department of General Practice and Primary Health Care University of Helsinki  Helsinki Finland"},{"name":"Unit of Primary Health Care Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7501-7996","authenticated-orcid":false,"given":"Agathe D.","family":"Jadczak","sequence":"additional","affiliation":[{"name":"Adelaide Geriatrics Training and Research with Aged Care (GTRAC) Centre, Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"},{"name":"The Basil Hetzel Institute, The Queen Elizabeth Hospital Central Adelaide Local Health Network  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna\u2010Maria","family":"Roitto","sequence":"additional","affiliation":[{"name":"Department of Geriatrics University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla L.","family":"Aalto","sequence":"additional","affiliation":[{"name":"Department of Geriatrics University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta K.T.","family":"Saarela","sequence":"additional","affiliation":[{"name":"Department of General Practice and Primary Health Care University of Helsinki  Helsinki Finland"},{"name":"Social Services, Health Care and Rescue Services Division, Oral Health Care City of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1303-9479","authenticated-orcid":false,"given":"Renuka","family":"Visvanathan","sequence":"additional","affiliation":[{"name":"Adelaide Geriatrics Training and Research with Aged Care (GTRAC) Centre, Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"},{"name":"Aged and Extended Care Services, The Queen Elizabeth Hospital Central Adelaide Local Health Network  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7308-0572","authenticated-orcid":false,"given":"Shin J.","family":"Liau","sequence":"additional","affiliation":[{"name":"Centre for Medicine Use and Safety (CMUS), Faculty of Pharmacy and Pharmaceutical Sciences Monash University  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6001-9211","authenticated-orcid":false,"given":"Amanda J.","family":"Cross","sequence":"additional","affiliation":[{"name":"Centre for Medicine Use and Safety (CMUS), Faculty of Pharmacy and Pharmaceutical Sciences Monash University  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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