{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T05:11:24Z","timestamp":1696569084155},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T00:00:00Z","timestamp":1353456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asia-Pac J Clncl Oncology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate whether axillary ultrasound in combination with a biopsy (<jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> +\/\u2212 <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x) can predict the involvement of the non\u2010sentinel lymph nodes (<jats:styled-content style=\"fixed-case\">NSLN<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A review of all operable breast cancer patients who underwent <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> +\/\u2212 <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x at our tertiary care center from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2010 to <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pril 2011 was performed. All patients underwent <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> as part of their pre\u2010operative evaluation. If the <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> was suspicious, a fine\u2010needle aspiration or core\u2010needle biopsy was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 88 patients included in our final analysis, 20 (23%) had positive <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content>\u2009+\u2009<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x and underwent axillary lymph node dissection (<jats:styled-content style=\"fixed-case\">ALND<\/jats:styled-content>) at time of definitive surgery. In all, 68 of the 88 patients (77.3%) had negative <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> +\/\u2212 <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x and underwent sentinel lymph node (<jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x at the time of definitive surgery. If the <jats:styled-content style=\"fixed-case\">SLN B<\/jats:styled-content>x was negative, no further axillary surgery was performed and the <jats:styled-content style=\"fixed-case\">NSLN<\/jats:styled-content> were assumed to be negative. If the <jats:styled-content style=\"fixed-case\">SLN B<\/jats:styled-content>x was positive, <jats:styled-content style=\"fixed-case\">ALND<\/jats:styled-content> was performed. Of the 68 patients, 62 (91%) had a negative <jats:styled-content style=\"fixed-case\">NSLN<\/jats:styled-content>. Patients with positive <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content>\u2009+\u2009<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x carry a relative risk of 2.02 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00002) of having positive <jats:styled-content style=\"fixed-case\">NSLN<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In operable breast cancer patients, a negative <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content>+\/\u2212 <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>x may be a predictor of non\u2010involvement of the <jats:styled-content style=\"fixed-case\">NSLN<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajco.12039","type":"journal-article","created":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T08:53:47Z","timestamp":1353488027000},"source":"Crossref","is-referenced-by-count":1,"title":["Negative axillary ultrasonography with biopsy may predict non\u2010involvement of the non\u2010sentinel lymph nodes in operable breast cancer patients"],"prefix":"10.1111","volume":"10","author":[{"given":"Muna","family":"Al Ayyan","sequence":"first","affiliation":[{"name":"Department of Surgery Tawam Hospital  Al\u2010Ain United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omaima","family":"Bu Ali","sequence":"additional","affiliation":[{"name":"Department of Surgery Tawam Hospital  Al\u2010Ain United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheikha","family":"Al Sharri","sequence":"additional","affiliation":[{"name":"Department of Surgery Tawam Hospital  Al\u2010Ain United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Kassis","sequence":"additional","affiliation":[{"name":"Department of Radiology Tawam Hospital  Al\u2010Ain United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabir","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of Oncology Tawam Hospital  Al\u2010Ain United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Al\u2010Bashir","sequence":"additional","affiliation":[{"name":"Department of Surgery Tawam Hospital  Al\u2010Ain United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,21]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"National Comprehensive Cancer Network.NCCN guidelines[cited 17 October 2012]. 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