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The management of each entity differs to some degree from their sporadic counterparts, while the lack of a genotype\u2010phenotype correlation requires lifelong clinical, biochemical and radiological screening for the development of new tumors. While the syndrome itself is relatively rare (a prevalence of 1\u201310\/100\u2009000), it is likely that health\u2010care practitioners from numerous specialities will occasionally encounter a patient with <jats:styled-content style=\"fixed-case\">MEN1<\/jats:styled-content> and therefore a basic knowledge of the syndrome is important. In addition, many of the associated tumors are seen commonly in sporadic form, and a judicious policy is therefore required in deciding how thoroughly patients who develop these tumors should be screened for <jats:styled-content style=\"fixed-case\">MEN1<\/jats:styled-content>. The current literature on <jats:styled-content style=\"fixed-case\">MEN1<\/jats:styled-content> is reviewed and key learning points are suggested for the clinician.<\/jats:p>","DOI":"10.1111\/ajco.12046","type":"journal-article","created":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T01:34:03Z","timestamp":1356572043000},"page":"297-309","source":"Crossref","is-referenced-by-count":24,"title":["<scp>M<\/scp>ultiple endocrine neoplasia type 1 (<scp>MEN1<\/scp>)"],"prefix":"10.1111","volume":"9","author":[{"given":"Richard W","family":"Carroll","sequence":"first","affiliation":[{"name":"Endocrine, Diabetes and Research Centre Wellington Regional Hospital  Wellington New 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