{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:01:50Z","timestamp":1792627310524,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,3,21]],"date-time":"2020-03-21T00:00:00Z","timestamp":1584748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asia-Pac J Clncl Oncology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study was to compare the prevalence of stoma\u2010related complications and stoma reversal perioperative complications of patients with low\u2010lying rectal cancer who received preventative loop ileostomy and those who underwent loop transverse colostomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective single\u2010center study analyzed the clinicopathologic and surgical data of 288 patients with pathologically proven primary rectal cancer who underwent anterior resection with either preventative loop ileostomy (<jats:italic>n<\/jats:italic> = 82) or loop transverse colostomy. To achieve comparability of a propensity score matching method was used to match patients from each group in a 1:2 ratio. Determinants of stoma\u2010related complications were analyzed by multivariate logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010nine (74.3%) patients in the loop ileostomy group experienced stoma\u2010related complications versus 48.7% in the loop transverse colostomy group (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01). Irritant dermatitis was the most frequent complication in both groups. The loop ileostomy group had a significantly higher rate (24.24%) of stoma reversal perioperative complications than the loop transverse colostomy group. Multivariate logistic regression analysis showed that ileostomy versus loop transverse colostomy was a significant independent risk for stoma\u2010related complications and stoma reversal perioperative complications. Furthermore, by Clavien\u2013Dindo classification, patients receiving loop ileostomy had an overall higher rate of complications and stoma reversal perioperative complications versus those undergoing loop transverse colostomy (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01). The rate of grade II complications was significantly higher in the loop ileostomy group (43.9%) than that of loop transverse colostomy group (13.5%, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01), whereas the rate of grade I, and grade IIIa and IIIb complications and stoma reversal perioperative complications was comparable between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study has demonstrated that loop transverse colostomy is associated with significantly lower rates of stoma\u2010related complications and stoma reversal perioperative complications compared to loop transverse colostomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajco.13322","type":"journal-article","created":{"date-parts":[[2020,3,21]],"date-time":"2020-03-21T17:24:47Z","timestamp":1584811487000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of safety of loop ileostomy and loop transverse colostomy for low\u2010lying rectal cancer patients undergoing anterior resection: A retrospective, single institution, propensity score\u2010matched study"],"prefix":"10.1111","volume":"19","author":[{"given":"Xiyu","family":"Sun","sequence":"first","affiliation":[{"name":"Department of General Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqiao","family":"Han","sequence":"additional","affiliation":[{"name":"Chinese Academy of Medical Sciences Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huizhong","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of General Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing 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