{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T19:21:55Z","timestamp":1784143315344,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T00:00:00Z","timestamp":1642982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asia-Pac J Clncl Oncology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess the image quality and delineation value of compressed sensing (CS)\u2010accelerated 3D T2W turbo\u2010spin\u2010echo (TSE) sequence for radiotherapy treatment planning (RTP) of prostate cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An optimized CS\u2010accelerated 3D\u2010T2W\u2010TSE was determined by volunteer imaging and applied for clinical RTP\u2010MRI. This optimized CS\u2010accelerated planning MRI and the standardized adaptive MRI acquired at 1.5T were retrospectively analyzed in 26 prostate cancer patients who were to receive MR\u2010guided radiotherapy. Signal\u2010to\u2010noise ratio (SNR) and relative contrast ratio (CR) were quantitatively assessed. Image quality and artifacts were qualitatively assessed using a five\u2010point scale rating. Delineation value in the prostate and organs\u2010at\u2010risk (OARs) was also rated and compared. Wilcoxon signed\u2010rank test was used for SNR, relative CR, and rating comparisons. The interobserver rating agreement was evaluated by percent agreement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significantly better SNR and relative CR in the prostate, rectum, bowel, penis, and penile bulb, while significantly worse in the cauda equina, were observed on the planning MRI. Significantly better ratings of image quality and artifacts were given to the planning MRI, with much less Gibbs ringing and reconstruction artifacts. Significantly better delineation value rating was achieved on the planning MRI in the prostate, seminal vesicle, rectum, penis, penile bulb, and testes, while significantly worse in the cauda equina. A strong to almost perfect interobserver rating agreement was obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggested that CS acceleration is applicable and valuable in prostate RTP\u2010MRI. CS\u2010accelerated 3D\u2010T2W\u2010TSE images should benefit the delineation of prostate and many OARs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajco.13752","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T20:47:53Z","timestamp":1643057273000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["3D\u2010T2W\u2010TSE radiotherapy treatment planning MRI using compressed sensing acceleration for prostate cancer: Image quality and delineation value"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6357-5010","authenticated-orcid":false,"given":"Oi Lei","family":"Wong","sequence":"first","affiliation":[{"name":"Research Department Hong Kong Sanatorium and Hospital  Hong Kong Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6226-0743","authenticated-orcid":false,"given":"Darren 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