{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T15:21:17Z","timestamp":1774279277695,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asia-Pac J Clncl Oncology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      <jats:sup>177<\/jats:sup>\n                      Lu\u2010PSMA radioligand therapy (RLT) is increasingly used to treat metastatic castration\u2010resistant prostate cancer (mCRPC). Posttreatment dosimetry is essential for assessing normal organ absorbed doses. Therefore, this study aims to evaluate normal organs dosimetry in mCRPC patients undergoing\n                      <jats:sup>177<\/jats:sup>\n                      Lu\u2010PSMA\u2010RLT from two university\u2010based hospitals in Thailand.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 61 treatment cycles in 36 patients who underwent posttreatment whole\u2010body planar imaging at three time points (1, 24, and 168\u00a0h postadministration). Absorbed doses were computed using organ based MIRD (Medical Internal Radiation Dosimetry) method with OLINDA\/EXM v.2.2 in Hermes dosimetry software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median treated activity was 5.79 GBq (range 5.00\u20137.29 GBq). Normal organ absorbed doses, from lowest to highest, were red marrow (0.03 \u00b1 0.03\u00a0Gy\/GBq), total body (0.04 \u00b1 0.03\u00a0Gy\/GBq), liver (0.13 \u00b1 0.33\u00a0Gy\/GBq), salivary glands (0.65 \u00b1 0.42\u00a0Gy\/GBq), and kidneys (0.72 \u00b1 0.36\u00a0Gy\/GBq).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Absorbed doses to normal organs remained within an acceptable range and not exceed the tolerance limits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajco.14187","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T04:29:26Z","timestamp":1747801766000},"page":"199-206","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Post\u2010Therapeutic Dosimetry of Metastatic Castration\u2010Resistant Prostate Cancer With\n                    <sup>177<\/sup>\n                    Lu\u2010PSMA: Experiences From Two University\u2010Based Hospitals in Thailand"],"prefix":"10.1111","volume":"22","author":[{"given":"Onnicha","family":"Pattanawong","sequence":"first","affiliation":[{"name":"Master of Science Program in Medical Physics Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Putthiporn","family":"Charoenphun","sequence":"additional","affiliation":[{"name":"Master of Science Program in Medical Physics Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"},{"name":"Division of Nuclear Medicine Department of Diagnostic and Therapeutic Radiology Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wichana","family":"Chamroonrat","sequence":"additional","affiliation":[{"name":"Division of Nuclear Medicine Department of Diagnostic and Therapeutic Radiology Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thonnapong","family":"Thongpraparn","sequence":"additional","affiliation":[{"name":"Division of Nuclear Medicine Department of Radiology Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nucharee","family":"Poon\u2010iad","sequence":"additional","affiliation":[{"name":"Division of Nuclear Medicine Department of Radiology Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjapa","family":"Khiewvan","sequence":"additional","affiliation":[{"name":"Division of Nuclear Medicine Department of Radiology Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0362-9125","authenticated-orcid":false,"given":"Krisanat","family":"Chuamsaamarkkee","sequence":"additional","affiliation":[{"name":"Master of Science Program in Medical Physics Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"},{"name":"Division of Nuclear Medicine Department of Diagnostic and Therapeutic Radiology Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_8_3_1","unstructured":"N.Mottet P.Cornford R. 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