{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T18:23:15Z","timestamp":1780078995358,"version":"3.54.0"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,18]],"date-time":"2013-01-18T00:00:00Z","timestamp":1358467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Proliferative nodules (<jats:styled-content style=\"fixed-case\">PN<\/jats:styled-content>) are benign lesions that arise in large congenital melanocytic naevi (<jats:styled-content style=\"fixed-case\">LCMN<\/jats:styled-content>). Clinically and histologically they can be difficult to differentiate from malignancies, which are also associated with <jats:styled-content style=\"fixed-case\">LCMN<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">PN<\/jats:styled-content> in this case consisted of undifferentiated spindle cells and exhibited unusual histological features including negative stains for melanocytic markers (<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>100, <jats:styled-content style=\"fixed-case\">HMB<\/jats:styled-content>45 and <jats:styled-content style=\"fixed-case\">MelA<\/jats:styled-content>), negative stain for c\u2010Kit, high mitotic index and unusual morphology of the lesional cells. As a result, a firm histological classification could not be made, which posed a challenge for the clinical management.<\/jats:p>","DOI":"10.1111\/ajd.12017","type":"journal-article","created":{"date-parts":[[2013,1,18]],"date-time":"2013-01-18T06:29:20Z","timestamp":1358490560000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Proliferative nodules of undifferentiated spindle cells arising in a large congenital melanocytic naevus"],"prefix":"10.1111","volume":"55","author":[{"given":"Elizabeth M","family":"Christou","sequence":"first","affiliation":[{"name":"Sydney Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew Chih\u2010Chieh","family":"Chen","sequence":"additional","affiliation":[{"name":"Royal Prince Alfred Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella","family":"Sugo","sequence":"additional","affiliation":[{"name":"Sydney Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Draga","family":"Barbaric","sequence":"additional","affiliation":[{"name":"Sydney Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orli","family":"Wargon","sequence":"additional","affiliation":[{"name":"Sydney Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1981.tb00954.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06316.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000122209.10277.2A"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70264-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(03)00090-0"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.01782.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000126785.61609.6e"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.1.83"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10502.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2007.02542.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198103000-00004"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12017","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T23:19:22Z","timestamp":1696461562000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,18]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/ajd.12017"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12017","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,18]]},"assertion":[{"value":"2012-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-11-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}