{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:34:14Z","timestamp":1791290054625,"version":"4.3.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T00:00:00Z","timestamp":1412899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Exposure to hair dye is the most frequent route of sensitisation to para\u2010phenylenediamine (<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>), a common contact allergen. International studies have examined the profile of <jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>, but Australian\u2010sourced information is lacking. Patients are often dissatisfied with advice to stop dyeing their hair. This study examines patients' characteristics, patch test results and outcomes of <jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content> allergy from a single Australian centre, through a retrospective analysis of patch test data from 2006 to 2013 at the Liverpool Hospital Dermatology Department. It reviews the science of hair dye allergy, examines alternative hair dyes and investigates strategies for hair dyeing. Of 584 patients, 11 were allergic to <jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content>. Our <jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content> allergy prevalence rate of 2% is at the lower end of international reported rates. About half these patients also react to para\u2010toluenediamine (<jats:styled-content style=\"fixed-case\">PTD<\/jats:styled-content>). Affected patients experience a significant lifestyle disturbance. In all, 78% tried alternative hair dyes after the patch test diagnosis and more than half continued to dye their hair. Alternative non\u2010<jats:styled-content style=\"fixed-case\">PPD<\/jats:styled-content> hair dyes are available but the marketplace can be confusing. Although some patients are able to tolerate alternative hair dyes, caution is needed as the risk of developing an allergy to other hair dye ingredients, especially <jats:styled-content style=\"fixed-case\">PTD<\/jats:styled-content>, is high.<\/jats:p>","DOI":"10.1111\/ajd.12189","type":"journal-article","created":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T14:08:41Z","timestamp":1412950121000},"page":"40-43","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Allergic contact dermatitis to para\u2010phenylenediamine"],"prefix":"10.1111","volume":"56","author":[{"given":"David","family":"Jenkins","sequence":"first","affiliation":[{"name":"Department of Dermatology Liverpool Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth T","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Dermatology Liverpool Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,10]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Fishers Contact Dermatitis","author":"Rietschel RL","year":"1995"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2010.11.011"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1263(199907\/08)19:4<255::AID-JAT573>3.0.CO;2-S"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06742.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09352.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajcd.2002.30466"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01704.x"},{"key":"e_1_2_7_9_1","unstructured":"European Commission.Opinion on Toluene\u20102 5\u2010diamine and its sulphate COLIPA n\u00b0 A5 SCCS\/1479\/12.2012. Available from URL:http:\/\/bookshop.europa.eu\/en\/opinion\u2010on\u2010toluene\u20102\u20105\u2010diamine\u2010and\u2010its\u2010sulfate\u2010pbNDAQ12016\/. (Accessed 7 Nov 2013.) Updated 18 September 2012."},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2310\/6620.2011.00010","article-title":"Alternative Hair\u2010dye products for persons allergic to para\u2010phenylenediamine","volume":"22","author":"Scheman A","year":"2011","journal-title":"Dermatitis"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12189","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12189","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:10:08Z","timestamp":1695471008000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,10]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1111\/ajd.12189"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12189","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,10]]},"assertion":[{"value":"2013-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-10-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}