{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T11:55:48Z","timestamp":1773834948205,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,12,13]],"date-time":"2014-12-13T00:00:00Z","timestamp":1418428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","award":["900399"],"award-info":[{"award-number":["900399"]}],"id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Hirsutism is defined as the excessive male\u2010pattern growth of hair in women. Hirsutism is often idiopathic or the consequence of polycystic ovary syndrome (<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>). Insulin resistance is common in <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> (especially in obese patients) but the association between insulin resistance and idiopathic hirsutism (<jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content>) is not clear. The aim of this study was to investigate the rate of insulin resistance in <jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content>, compared with healthy individuals and patients with <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included three groups, patients with idiopathic hirsutism, <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> and healthy women. Each group included 30 non\u2010obese women. Fasting blood sugar (<jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content>), insulin level and insulin resistance (estimated by the homeostasis model assessment [<jats:styled-content style=\"fixed-case\">HOMA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IRIR<\/jats:styled-content>]) were compared in the three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant difference between the age of the women with <jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content> compared with two other groups. There were no significant difference in levels of serum insulin (<jats:italic>P<\/jats:italic>\u2009=\u20090.49, <jats:styled-content style=\"fixed-case\">HOMA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IR<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u2009=\u20090.47) and prevalence of insulin resistance (<jats:italic>P<\/jats:italic>\u2009=\u20090.07) in the three groups. The age\u2010adjusted prevalence of insulin resistance was similar in the three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Insulin resistance was no more frequent in <jats:styled-content style=\"fixed-case\">IH<\/jats:styled-content> patients than in healthy control groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.12276","type":"journal-article","created":{"date-parts":[[2014,12,13]],"date-time":"2014-12-13T07:21:34Z","timestamp":1418455294000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of insulin resistance in idiopathic hirsutism compared with polycystic ovary syndrome patients and healthy individuals"],"prefix":"10.1111","volume":"57","author":[{"given":"Shokoufeh","family":"Bonakdaran","sequence":"first","affiliation":[{"name":"Endocrine Research Centre Ghaem Hospital Mashhad University of Medical Science  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bita","family":"Kiafar","sequence":"additional","affiliation":[{"name":"Skin Ward Emam Reza Hospital Mashhad University of Medical Science  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Barazandeh Ahmadabadi","sequence":"additional","affiliation":[{"name":"Endocrine Research Centre Ghaem Hospital Mashhad University of Medical Science  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.21.4.347"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031122"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03343881"},{"key":"e_1_2_7_5_1","first-page":"380","volume-title":"Harrison's Principles of Internal Medicine","author":"Ehrmann DA","year":"2012"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh098"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2014.02.007"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)48320-2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)03111-4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2012.28563"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.117430"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031626"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ11-0101"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09078.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000096434"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2013.797399"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12276","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12276","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T18:25:07Z","timestamp":1694283907000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,13]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/ajd.12276"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12276","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,13]]},"assertion":[{"value":"2014-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-10-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-12-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}