{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T14:44:23Z","timestamp":1750344263048},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,2,25]],"date-time":"2015-02-25T00:00:00Z","timestamp":1424822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with a history of non\u2010melanoma skin cancer (<jats:styled-content style=\"fixed-case\">NMSC<\/jats:styled-content>) have a 50% risk of developing subsequent <jats:styled-content style=\"fixed-case\">NMSC<\/jats:styled-content>.<jats:sup>13<\/jats:sup> Currently there are limited data on the association between multiple squamous cell carcinomas (<jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>) and the risk of other cancers, including melanomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the risk factors in a cohort of 210 <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralians with a history of multiple invasive <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>, focusing on the association between multiple <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> and other cancers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected from patients of a private practice in south\u2010east <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ueensland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A fair complexion and childhood sun exposure were found to be common in this cohort. Approximately half the patients who had their first <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> at or before the age of 30 years subsequently developed a melanoma. There was also an increased risk of internal cancer, prostate cancer being the commonest, followed by bowel and breast cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with a history of multiple invasive <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content> should be aware of their increased risk of future <jats:styled-content style=\"fixed-case\">NMSC<\/jats:styled-content> and of melanomas. The results of thisstudy suggest such patients and their care providers should also consider an appropriate screening for internal malignancies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.12278","type":"journal-article","created":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T04:38:05Z","timestamp":1424925485000},"page":"29-32","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["An <scp>A<\/scp>ustralian cohort of 210 patients with multiple invasive squamous cell carcinomas: risk factors and associated increased risk of melanoma and internal malignancies"],"prefix":"10.1111","volume":"57","author":[{"given":"Parastoo","family":"Banan","sequence":"first","affiliation":[{"name":"Dermatology Research Centre The University of Queensland School of Medicine, Translational Research Institute  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salman 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