{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:16:54Z","timestamp":1780539414432,"version":"3.54.1"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T00:00:00Z","timestamp":1425513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report an unusual case of <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>erkel cell carcinoma in a 70\u2010year\u2010old woman with the rapid development of left upper limb in\u2010transit and hepatic metastases. The patient had a preceding history of left\u2010sided breast cancer. Palliative chemotherapy with carboplatin and etoposide produced a minimal response. The in\u2010transit metastases rapidly progressed and were refractory to chemotherapy and a single fraction of palliative radiotherapy, leading to a marked impact on her quality of life, secondary to sepsis and bleeding. After lengthy discussion, she consented to an above\u2010elbow amputation resulting in a marked improvement in her well\u2010being. In this case, we believe that palliative amputation of the involved arm was justified and beneficial to the patient.<\/jats:p>","DOI":"10.1111\/ajd.12291","type":"journal-article","created":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T11:25:12Z","timestamp":1425554712000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["<scp>M<\/scp>erkel cell carcinoma: A case of palliative upper limb amputation in a patient with refractory in\u2010transit metastases"],"prefix":"10.1111","volume":"57","author":[{"given":"Dakshika A","family":"Gunaratne","sequence":"first","affiliation":[{"name":"Department of Surgery Crown Princess Mary Cancer Care Centre Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie R","family":"Howle","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology Crown Princess Mary Cancer Care Centre Westmead Hospital  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J","family":"Veness","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology and Crown Princess Mary Cancer Care Centre Westmead Hospital  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000029"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.01883.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e31829e3566"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12481"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.04.042"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31822c5fc1"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0985-4"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12291","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12291","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T17:48:10Z","timestamp":1695491290000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,5]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/ajd.12291"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12291","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,5]]},"assertion":[{"value":"2014-10-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-11-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}