{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:51:58Z","timestamp":1761630718847,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,3,31]],"date-time":"2015-03-31T00:00:00Z","timestamp":1427760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>Solar (actinic) keratosis (<jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>) is an emergent concern worldwide and is associated with an increased risk of development of non\u2010melanoma skin cancer, especially squamous cell carcinoma. Daylight\u2010mediated photodynamic therapy (<jats:styled-content style=\"fixed-case\">DL\u2010PDT<\/jats:styled-content>) using methyl aminolaevulinate cream has proved to be an effective, nearly painless, and more convenient alternative to conventional <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> for the treatment of <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>. In a phase <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, randomised, controlled trial performed in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, the mean irradiance (light intensity) received by patients during <jats:styled-content style=\"fixed-case\">DL\u2010PDT<\/jats:styled-content> treatment, assessed via a spectroradiometer, was 305\u2009W\/m<jats:sup>2<\/jats:sup> (min. 40 to max. 585\u2009W\/m<jats:sup>2<\/jats:sup>) with similar efficacy irrespective of intensity or dose. The objective of the present meteorological study was to assess the suitability of natural daylight to perform <jats:styled-content style=\"fixed-case\">DL\u2010PDT<\/jats:styled-content> for the treatment of face and scalp <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> during different periods of the year and different geographical locations and latitudes across <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>To determine daylight irradiance during a complete year in eight different geographical locations throughout <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, we used meteorological software (<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>eteonorm, <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>eteotest, <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>ern, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>witzerland), and available solar radiation and weather data from 1986\u20132005.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average daily irradiance remained within the levels (40\u2013585\u2009W\/m<jats:sup>2<\/jats:sup>) measured during the clinical <jats:styled-content style=\"fixed-case\">DL\u2010PDT<\/jats:styled-content> study in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, throughout the year and in all geographical locations investigated (yearly average from <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>arwin 548\u2009W\/m<jats:sup>2<\/jats:sup> to <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>obart 366\u2009W\/m<jats:sup>2<\/jats:sup>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DL\u2010PDT<\/jats:styled-content> for the treatment of face and scalp <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia can be performed effectively throughout the entire year as long as weather conditions permit daylight exposure and allow participants to remain under direct light for 2\u2009h.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.12295","type":"journal-article","created":{"date-parts":[[2015,4,2]],"date-time":"2015-04-02T19:50:40Z","timestamp":1428004240000},"page":"24-28","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Treatment of face and scalp solar (actinic) keratosis with daylight\u2010mediated photodynamic therapy is possible throughout the year in <scp>A<\/scp>ustralia: Evidence from a clinical and meteorological study"],"prefix":"10.1111","volume":"57","author":[{"given":"Lynda","family":"Spelman","sequence":"first","affiliation":[{"name":"Specialist Connect  Woolloongabba Queensland Australia"},{"name":"Probity Medical Research Inc.  Waterloo Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Rubel","sequence":"additional","affiliation":[{"name":"Woden Dermatology  Canberra, ACT Australia"},{"name":"Probity Medical Research Inc.  Waterloo Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dedee F","family":"Murrell","sequence":"additional","affiliation":[{"name":"Sydney and University of NSW  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u2010Ann","family":"See","sequence":"additional","affiliation":[{"name":"Central Sydney Dermatology  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Hewitt","sequence":"additional","affiliation":[{"name":"Skin and Cancer Foundation  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Foley","sequence":"additional","affiliation":[{"name":"Skin and Cancer Foundation Inc.  Victoria Australia"},{"name":"University of Melbourne  Victoria Australia"},{"name":"St Vincent's Hospital, Melbourne  Victoria Australia"},{"name":"Probity Medical Research Inc.  Waterloo Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Salmon","sequence":"additional","affiliation":[{"name":"Illawarra Dermatology and Laser Clinic  Wollongong New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delphine","family":"Kerob","sequence":"additional","affiliation":[{"name":"Galderma International  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Pascual","sequence":"additional","affiliation":[{"name":"Galderma R&amp;D SNC  Sophia Antipolis France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Shumack","sequence":"additional","affiliation":[{"name":"St George Dermatology and Skin Cancer Centre  Sydney New South Wales Australia"},{"name":"Probity Medical Research Inc.  Waterloo Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4882-1564","authenticated-orcid":false,"given":"Pablo","family":"Fernandez\u2010Penas","sequence":"additional","affiliation":[{"name":"Westmead Clinical School Westmead Hospital University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,31]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"529","article-title":"Data analysis of the Brazilian Society of Dermatology skin cancer prevention campaign, 1999 to 2005","volume":"81","author":"Sociedade Brasileira de Dermatologia","year":"2006","journal-title":"An. Bras. Dermatol."},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03541.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb08544.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12031"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07692.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08450.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09119.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10209.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1425"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10833.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04386.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13138"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11200.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0038-092X(98)00020-6"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2011.00611.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04386.x"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12295","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12295","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12295","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajd.12295","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T18:25:02Z","timestamp":1694283902000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,31]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/ajd.12295"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12295","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"type":"print","value":"0004-8380"},{"type":"electronic","value":"1440-0960"}],"subject":[],"published":{"date-parts":[[2015,3,31]]},"assertion":[{"value":"2014-06-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-11-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}