{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T14:12:14Z","timestamp":1774620734984,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,8,24]],"date-time":"2015-08-24T00:00:00Z","timestamp":1440374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>gent <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>lue was an arsenical herbicide used extensively in the <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>ietnam <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>ar. Arsenic is one of the known causes of acquired palmoplantar keratoderma (<jats:styled-content style=\"fixed-case\">PPK<\/jats:styled-content>). The most common manifestation of arsenic exposure in susceptible individuals is bilateral palmoplantar hyperkeratosis. We report a 67\u2010year\u2010old man with no known prior exposure to arsenic in the <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content> or family history of <jats:styled-content style=\"fixed-case\">PPK<\/jats:styled-content> who developed multiple squamous cell carcinoma <jats:italic>in situ<\/jats:italic> (<jats:styled-content style=\"fixed-case\">SCCIS<\/jats:styled-content>) and palmoplantar hyperkeratotic lesions beginning 23 years after service in <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>ietnam. The <jats:styled-content style=\"fixed-case\">SCCIS<\/jats:styled-content> were located on the trunk and extremities in both sun\u2010exposed and non\u2010sun\u2010exposed sites and his palmoplantar lesions were diagnosed concurrently with his <jats:styled-content style=\"fixed-case\">SCCIS<\/jats:styled-content>. He has continued to develop <jats:styled-content style=\"fixed-case\">SCCIS<\/jats:styled-content> since his first visit to our clinic 25 years ago.<\/jats:p>","DOI":"10.1111\/ajd.12387","type":"journal-article","created":{"date-parts":[[2015,8,24]],"date-time":"2015-08-24T11:29:12Z","timestamp":1440415752000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Palmoplantar keratoses and <scp>B<\/scp>owen's disease in a <scp>V<\/scp>ietnam veteran: Could <scp>A<\/scp>gent <scp>B<\/scp>lue be implicated?"],"prefix":"10.1111","volume":"57","author":[{"suffix":"Jr","given":"Armand B","family":"Cognetta","sequence":"first","affiliation":[{"name":"Division of Dermatology Florida State University College of Medicine  Tallahassee Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M","family":"Wolfe","sequence":"additional","affiliation":[{"name":"Division of Dermatology Florida State University College of Medicine  Tallahassee Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander T","family":"Herbst","sequence":"additional","affiliation":[{"name":"Division of Dermatology Florida State University College of Medicine  Tallahassee Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01537"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200708010-00001"},{"key":"e_1_2_6_4_1","volume-title":"Examination of the Potential Exposure of Royal Australian Navy (RAN) Personnel to Polychlorinated Dibenzodioxins and Polychlorinated dibenzofurans via Drinking Water","author":"Muller J","year":"2002"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(00)00458-3"},{"key":"e_1_2_6_6_1","unstructured":"CaussyD(ed.).A field guide for detection management and surveillance of arsenicosis cases. 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