{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:22:22Z","timestamp":1740126142910,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T00:00:00Z","timestamp":1448409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"Abstract<\/jats:title>Coccidioidomycosis is an endemic fungal infection in the southwestern USA<\/jats:styled-content> and northern M<\/jats:styled-content>exico. It is caused by C<\/jats:italic><\/jats:styled-content>occidioides immitis<\/jats:italic> and C<\/jats:italic><\/jats:styled-content>. posadasii.<\/jats:italic> This infection occurs due to the inhalation of airborne arthroconidia, causing a mild pulmonary infection, but most cases are asymptomatic. Disseminated coccidioidomycosis (DC<\/jats:styled-content>) is a rare entity occurring in less than 1% of all cases, usually in immunocompromised patients, and it carries high risks of morbidity and mortality. The skin is one of the most frequently affected organs and in some cases cutaneous lesions may be the first or only sign of infection. A wide spectrum of clinical lesions may develop, including cold abscess. In immunocompromised hosts, DC<\/jats:styled-content> represents a diagnostic and therapeutic challenge. Treatment is based on antifungal drugs, such as amphotericin B<\/jats:styled-content> and azoles, administered for long periods of time and under close follow up to monitor the treatment response and to detect relapse. In the following case report, we present a 35\u2010year\u2010old male patient with systemic lupus erythematosus under immunosuppressive therapy who presented with cold subcutaneous abscesses as the first sign of DC<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/ajd.12424","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T03:25:01Z","timestamp":1448508301000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cold subcutaneous abscesses as the first manifestation of disseminated coccidioidomycosis in an immunocompromised host"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4690-0421","authenticated-orcid":false,"given":"Juana Irma","family":"Garza\u2010Chapa","sequence":"first","affiliation":[{"name":"Dermatology Service University Hospital \u2018Dr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u2019 Universidad Auton\u00f3ma de Nuevo Le\u00f3n Monterrey M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvia Aide","family":"Mart\u00ednez\u2010Cabriales","sequence":"additional","affiliation":[{"name":"Dermatology Service University Hospital \u2018Dr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u2019 Universidad Auton\u00f3ma de Nuevo Le\u00f3n Monterrey M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Ocampo\u2010Garza","sequence":"additional","affiliation":[{"name":"Dermatology Service University Hospital \u2018Dr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u2019 Universidad Auton\u00f3ma de Nuevo Le\u00f3n Monterrey M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minerva","family":"G\u00f3mez\u2010Flores","sequence":"additional","affiliation":[{"name":"Dermatology Service University Hospital \u2018Dr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u2019 Universidad Auton\u00f3ma de Nuevo Le\u00f3n Monterrey M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Ocampo\u2010Candiani","sequence":"additional","affiliation":[{"name":"Dermatology Service University Hospital \u2018Dr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u2019 Universidad Auton\u00f3ma de Nuevo Le\u00f3n Monterrey M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliverio","family":"Welsh","sequence":"additional","affiliation":[{"name":"Dermatology Service University Hospital \u2018Dr. Jos\u00e9 Eleuterio Gonz\u00e1lez\u2019 Universidad Auton\u00f3ma de Nuevo Le\u00f3n Monterrey M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,11,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.031"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2012.01.003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1477-8939(03)00011-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2012.02855.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000259231.95285.bc"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21784"},{"key":"e_1_2_6_8_1","first-page":"733","article-title":"Cold subcutaneous abscesses","volume":"82","author":"Jackson R","year":"1990","journal-title":"J. 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