{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T14:53:08Z","timestamp":1785509588411,"version":"3.56.0"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T00:00:00Z","timestamp":1503532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"Abstract<\/jats:title>Background\/Objectives<\/jats:title>Atopic dermatitis (AD<\/jats:styled-content>) is a common condition affecting up to 20% of the paediatric population in Singapore. It is often associated with significant psychosocial morbidity and can affect patients' quality of life (QOL<\/jats:styled-content>) tremendously. This study investigated the varying lifestyle impacts, and psychosocial domains most affected by AD<\/jats:styled-content> in adolescent children in Singapore.<\/jats:p><\/jats:sec>Methods<\/jats:title>A prospective study evaluating the impact of AD<\/jats:styled-content> on the QOL<\/jats:styled-content> of adolescents was conducted over a 6\u2010month period from July to December 2014. Adolescents aged 11\u201316\u00a0years with varying eczema severity were recruited. Eczema severity was determined by using the eczema area and severity index (EASI<\/jats:styled-content>) scores. Lifestyle impact of AD<\/jats:styled-content> was evaluated using patient\u2010reported children's dermatology life quality index (CDLQI<\/jats:styled-content>) scores. Statistical analysis was performed using an analysis of one\u2010way variance and Student's t<\/jats:italic>\u2010test.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 50 patients were enrolled and divided into three groups: mild (<10.3), moderate (10.3\u201320.9) and severe (>20.9) eczema based on EASI<\/jats:styled-content> scores. Patients with mild and moderate eczema had lower CDLQI<\/jats:styled-content> scores. Adolescents were most affected by the disruption that their symptoms had on their leisure and physical activities and sleep as a result of itch and scratching, respectively.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Chronic sufferers of severe eczema experience poorer QOL<\/jats:styled-content> than those with mild or moderate eczema. They also experience significant psychosocial impact as a consequence of their condition.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.12632","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T05:11:59Z","timestamp":1503551519000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Effect of atopic dermatitis on quality of life and its psychosocial impact in Asian adolescents"],"prefix":"10.1111","volume":"59","author":[{"given":"Michelle SY","family":"Ng","sequence":"first","affiliation":[{"name":"Dermatology Service KK Women's and Children's Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyun","family":"Tan","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole HQ","family":"Chan","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice YW","family":"Foong","sequence":"additional","affiliation":[{"name":"Dermatology Service KK Women's and Children's Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark JA","family":"Koh","sequence":"additional","affiliation":[{"name":"Dermatology Service KK Women's and Children's Hospital Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04566.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01295.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.01047.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13662"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02034.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1998.tb01333.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb08530.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb16953.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155500300012873"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550410023284"},{"key":"e_1_2_7_12_1","volume-title":"Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem","author":"Colten HR","year":"2006"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1972.tb05072.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.69.6.670"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992287901800609"},{"key":"e_1_2_7_16_1","first-page":"416","article-title":"The psychosocial status of patients with endogenous eczema. 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