{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:14:21Z","timestamp":1759335261425,"version":"3.37.3"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T00:00:00Z","timestamp":1529625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>There is a paucity of Australian data on the use of Mohs micrographic surgery for treating melanoma <jats:italic>in situ<\/jats:italic> and lentigo maligna. We share an Australian centre's experience with the technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 62 patients with 62 lesions of melanoma <jats:italic>in situ<\/jats:italic> and lentigo maligna referred for treatment between 2015 and 2017 comprised the study group. All melanomas were excised with Mohs micrographic surgery utilising melanoma\u2010associated antigen recognised by T\u2010cells (<jats:styled-content style=\"fixed-case\">MART<\/jats:styled-content>\u20101) immunostaining.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Follow up ranged from 3 to 30 months with no reported recurrences or melanoma\u2010related deaths. 94% (58\/62) of lesions were primary melanomas and 6% were locally recurrent. 89% of lesions involved head and neck sites with 11% involving trunk or limbs. In total 55% (12\/62) of lesions were cleared with 3\u2010mm clinical margins, 68% with 6 mm, 92% with 9 mm and 100% with 12\u2010mm. The mean clinical excision margin was 6.7 mm. All lesions with a tumour diameter greater than 2.2 cm required a 9\u2010mm clinical margin or greater for excision. The mean clinical excision margin for recurrent tumours was 9 mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We provide the first Australian data on the use of Mohs micrographic surgery for melanoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.12845","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T09:20:00Z","timestamp":1529659200000},"page":"33-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Treating melanoma <i>in situ<\/i> and lentigo maligna with Mohs micrographic surgery in Australia"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6353-825X","authenticated-orcid":false,"given":"Glen C","family":"Foxton","sequence":"first","affiliation":[{"name":"South Perth Specialist Skin Cancer Centre Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy G","family":"Elliott","sequence":"additional","affiliation":[{"name":"South Perth Specialist Skin Cancer Centre Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly A","family":"Litterick","sequence":"additional","affiliation":[{"name":"South Perth Specialist Skin Cancer Centre Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,22]]},"reference":[{"volume-title":"Clinical Practice Guidelines for the Management of Melanoma in Australia and New Zealand","year":"2008","author":"Australian Cancer Network Melanoma Guidelines Revision Working Party","key":"e_1_2_5_2_1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198403000-00030"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.06.009"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2012.04.010"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000725"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.6138"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.06.033"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.007"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000248"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12335"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20305"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.08.038"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10227-002-1161-7"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)80131-4"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12356"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.02.011"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01432.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.00081.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.10.039"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.7.871"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31819d3769"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199912000-00006"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000152014.89434.96"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000756"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12845","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12845","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T16:32:35Z","timestamp":1694709155000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,22]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/ajd.12845"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12845","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"type":"print","value":"0004-8380"},{"type":"electronic","value":"1440-0960"}],"subject":[],"published":{"date-parts":[[2018,6,22]]},"assertion":[{"value":"2018-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}