{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:29:06Z","timestamp":1790281746335,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T00:00:00Z","timestamp":1534982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"Abstract<\/jats:title>Several case reports and cohort studies have recently investigated the potential association between bullous pemphigoid (BP<\/jats:styled-content>) and psoriasis. It has been speculated that chronic inflammation in the dermo\u2010epidermal junction can trigger exposure to antigens to autoreactive T cells, resulting in autoimmune blistering disease. However, the association described has been inconsistently reported amongst studies. We performed a systematic review and meta\u2010analysis to investigation this potential association. We identified four case\u2013control studies for inclusion in the present meta\u2010analysis, with a total of 4035 bullous pemphigoid cases and 19 215 control cases. There was a significantly higher prevalence of psoriasis in BP<\/jats:styled-content> compared to controls (2.6% vs<\/jats:italic> 1.1%, OR<\/jats:styled-content> 2.5, 95% CI<\/jats:styled-content> 1.4\u20134.6). Subgroup analysis showed that this association remained significant in both males (3.0% vs<\/jats:italic> 1.3%, OR<\/jats:styled-content> 2.4, 95% CI<\/jats:styled-content> 1.6\u20133.6) as well as females (1.9% vs<\/jats:italic> 0.7%, OR<\/jats:styled-content> 2.9, 95% CI<\/jats:styled-content> 1.4\u20135.9). A significantly higher proportion of cases were reported in males (3.0% vs<\/jats:italic> 1.9%, OR<\/jats:styled-content> 1.75, 95% CI<\/jats:styled-content> 1.1\u20132.7). This pooled analysis of existing case\u2013control studies to date demonstrates a significant association between BP<\/jats:styled-content> and psoriasis. We also showed that in contrast with the majority of autoimmune diseases which are predisposed in females, that the coexistence of BP<\/jats:styled-content> and psoriasis appears to be predisposed in male patients.<\/jats:p>","DOI":"10.1111\/ajd.12899","type":"journal-article","created":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T06:25:28Z","timestamp":1535091928000},"page":"23-28","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Association between bullous pemphigoid and psoriasis: Systematic review and meta\u2010analysis of case\u2010control studies"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5940-3555","authenticated-orcid":false,"given":"Kevin","family":"Phan","sequence":"first","affiliation":[{"name":"Department of Dermatology Liverpool Hospital Sydney New South Wales Australia"},{"name":"University of New South Wales Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7480-865X","authenticated-orcid":false,"given":"Sourabh","family":"Goyal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Lake Erie College of Osteopathic Medicine Erie Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dedee F","family":"Murrell","sequence":"additional","affiliation":[{"name":"University of New South Wales Sydney New South Wales Australia"},{"name":"Department of Dermatology St George Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,23]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"246","article-title":"Psoriasis with superimposed bullous eruption","volume":"130","author":"Bloom D","year":"1929","journal-title":"Med. 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